3ERD

HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE

Replaces:  2ERD

Summary for 3ERD

• Entry DOI: 10.2210/pdb3erd/pdb
• Descriptor: ESTROGEN RECEPTOR ALPHA, GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: nuclear receptor, transcription factor, estrogen, agonist, coactivator
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 63552.42

Authors

Shiau, A.K.,Barstad, D.,Loria, P.M.,Cheng, L.,Kushner, P.J.,Agard, D.A.,Greene, G.L. (deposition date: 1999-03-31, release date: 1999-04-08, Last modification date: 2023-09-06)

• Primary citation: Shiau, A.K.,Barstad, D.,Loria, P.M.,Cheng, L.,Kushner, P.J.,Agard, D.A.,Greene, G.L.; The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.; Cell(Cambridge,Mass.), 95:927-937, 1998; PubMed: 9875847; DOI: 10.1016/S0092-8674(00)81717-1

Experimental method

X-RAY DIFFRACTION (2.03 Å)