5T0E
 
 | | Crystal structure of H6 hemagglutinin G225D mutant from Taiwan (2013) H6N1 influenza virus in complex with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... | | Authors: | Wilson, I.A, Tzarum, N, Zhu, X. | | Deposit date: | 2016-08-15 | | Release date: | 2017-06-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
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5T08
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5T0B
 | | Crystal structure of H6 hemagglutinin G225D mutant from Taiwan (2013) H6N1 influenza virus in complex with 6'-SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... | | Authors: | Wilson, I.A, Tzarum, N, Zhu, X. | | Deposit date: | 2016-08-15 | | Release date: | 2017-06-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
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1QQE
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1R4X
 | | Crystal Structure Analys of the Gamma-COPI Appendage domain | | Descriptor: | Coatomer gamma subunit, MAGNESIUM ION | | Authors: | Watson, P.J, Frigerio, G, Collins, B.M, Duden, R, Owen, D.J. | | Deposit date: | 2003-10-09 | | Release date: | 2003-10-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
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6MSM
 | | Phosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | | Authors: | Zhang, Z, Liu, F, Chen, J. | | Deposit date: | 2018-10-16 | | Release date: | 2018-11-21 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular structure of the ATP-bound, phosphorylated human CFTR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5UAK
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6MRC
 | | ADP-bound human mitochondrial Hsp60-Hsp10 football complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | | Deposit date: | 2018-10-12 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.
Nat Commun, 11, 2020
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5TV1
 | | active arrestin-3 with inositol hexakisphosphate | | Descriptor: | Beta-arrestin-2, GLYCEROL, INOSITOL HEXAKISPHOSPHATE | | Authors: | Chen, Q, Gilbert, N.C, Perry, N.A, Vishniveteskiy, S, Gurevich, V.V, Iverson, T.M. | | Deposit date: | 2016-11-07 | | Release date: | 2017-11-22 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of arrestin-3 activation and signaling.
Nat Commun, 8, 2017
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6MRD
 | | ADP-bound human mitochondrial Hsp60-Hsp10 half-football complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | | Deposit date: | 2018-10-12 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.
Nat Commun, 11, 2020
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6S7P
 | | Nucleotide bound ABCB4 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... | | Authors: | Olsen, J.A, Alam, A, Kowal, J, Stieger, B, Locher, K.P. | | Deposit date: | 2019-07-05 | | Release date: | 2019-12-25 | | Last modified: | 2020-01-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of the human lipid exporter ABCB4 in a lipid environment.
Nat.Struct.Mol.Biol., 27, 2020
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1SKO
 | | MP1-p14 Complex | | Descriptor: | Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1 | | Authors: | Lunin, V.V, Munger, C, Wagner, J, Ye, Z, Cygler, M, Sacher, M. | | Deposit date: | 2004-03-05 | | Release date: | 2004-06-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of the MAP kinase scaffold MP1 bound to its partner p14: a complex with a critical role in endosomal MAP kinase signaling
J.Biol.Chem., 279, 2004
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6O2P
 | | Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR) | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | | Authors: | Liu, F, Zhang, Z, Chen, J, Levit, A, Shoichet, B. | | Deposit date: | 2019-02-24 | | Release date: | 2019-06-26 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural identification of a hotspot on CFTR for potentiation.
Science, 364, 2019
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6O1V
 | | Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | | Authors: | Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B. | | Deposit date: | 2019-02-21 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural identification of a hotspot on CFTR for potentiation.
Science, 364, 2019
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6NZ0
 | | Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2 | | Descriptor: | Capsid protein VP1, Dyslexia-associated protein KIAA0319-like protein, MAGNESIUM ION | | Authors: | Meyer, N.L, Xie, Q, Davulcu, O, Yoshioka, C, Chapman, M.S. | | Deposit date: | 2019-02-12 | | Release date: | 2019-06-12 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR.
Elife, 8, 2019
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1TFP
 | | TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN) | | Descriptor: | SULFATE ION, TRANSTHYRETIN | | Authors: | Sunde, M, Richardson, S.J, Chang, L, Pettersson, T.M, Schreiber, G, Blake, C.C.F. | | Deposit date: | 1996-01-05 | | Release date: | 1996-06-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of transthyretin from chicken.
Eur.J.Biochem., 236, 1996
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6ONA
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5WP9
 | | Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1 | | Descriptor: | Dynamin-1-like protein, MAGNESIUM ION, Mitochondrial dynamics protein MID49, ... | | Authors: | Kalia, R, Wang, R.Y.R, Yusuf, A, Thomas, P.V, Agard, D.A, Shaw, J.M, Frost, A. | | Deposit date: | 2017-08-03 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.22 Å) | | Cite: | Structural basis of mitochondrial receptor binding and constriction by DRP1.
Nature, 558, 2018
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1TQZ
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4V24
 | | Sphingosine kinase 1 in complex with PF-543 | | Descriptor: | ACETATE ION, SPHINGOSINE KINASE 1, {(2R)-1-[4-({3-METHYL-5-[(PHENYLSULFONYL)METHYL]PHENOXY}METHYL)BENZYL]PYRROLIDIN-2-YL}METHANOL | | Authors: | Elkins, J.M, Wang, J, Sorrell, F, Tallant, C, Wang, D, Shrestha, L, Bountra, C, von Delft, F, Knapp, S, Edwards, A. | | Deposit date: | 2014-10-05 | | Release date: | 2014-10-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Sphingosine Kinase 1 with Pf-543.
Acs Med.Chem.Lett., 5, 2014
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7A0V
 | | Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody | | Descriptor: | GLYCEROL, MAGNESIUM ION, Nanobody 13015, ... | | Authors: | Paesmans, J, Galicia, C, Martin, E, Versees, W. | | Deposit date: | 2020-08-11 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
Elife, 9, 2020
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7A17
 | | Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody | | Descriptor: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, GLYCEROL, Isoform 2 of Synaptojanin-1, ... | | Authors: | Paesmans, J, Galicia, C, Martin, E, Versees, W. | | Deposit date: | 2020-08-12 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
Elife, 9, 2020
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4WSU
 | | The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | Deposit date: | 2014-10-28 | | Release date: | 2015-02-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
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4WSX
 | | The crystal structure of hemagglutinin from A/Jiangxi-Donghu/346/2013 influenza virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | Authors: | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | Deposit date: | 2014-10-28 | | Release date: | 2015-02-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
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4WSV
 | | The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 6'SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | Deposit date: | 2014-10-28 | | Release date: | 2015-02-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
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