1SKO

MP1-p14 Complex

Summary for 1SKO
DescriptorMitogen-activated protein kinase kinase 1 interacting protein 1, Late endosomal/lysosomal Mp1 interacting protein (3 entities in total)
Functional Keywordsmap kinase pathway, mp1-p14 complex, scaffold proteins, signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationLate endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q9UHA4
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side: Q9JHS3
Total number of polymer chains2
Total formula weight30145.28
Authors
Lunin, V.V.,Munger, C.,Wagner, J.,Ye, Z.,Cygler, M.,Sacher, M. (deposition date: 2004-03-05, release date: 2004-06-01, Last modification date: 2011-07-13)
Primary citationCygler, M.,Lunin, V.V.,Munger, C.,Sacher, M.,Wagner, J.,Ye, Z.
The structure of the MAP kinase scaffold MP1 bound to its partner p14: a complex with a critical role in endosomal MAP kinase signaling
J.Biol.Chem., 279:23422-23430, 2004
PubMed: 15016825
DOI: 110.1074/jbc.M401648200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-09