1SKO

MP1-p14 Complex

Summary for 1SKO

Entry DOI	10.2210/pdb1sko/pdb
Descriptor	Mitogen-activated protein kinase kinase 1 interacting protein 1, Late endosomal/lysosomal Mp1 interacting protein (3 entities in total)
Functional Keywords	map kinase pathway, mp1-p14 complex, scaffold proteins, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Late endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q9UHA4 Late endosome membrane; Peripheral membrane protein; Cytoplasmic side: Q9JHS3
Total number of polymer chains	2
Total formula weight	30145.28
Authors	Lunin, V.V.,Munger, C.,Wagner, J.,Ye, Z.,Cygler, M.,Sacher, M. (deposition date: 2004-03-05, release date: 2004-06-01, Last modification date: 2024-02-14)
Primary citation	Lunin, V.V.,Munger, C.,Wagner, J.,Ye, Z.,Cygler, M.,Sacher, M. The structure of the MAP kinase scaffold MP1 bound to its partner p14: a complex with a critical role in endosomal MAP kinase signaling J.Biol.Chem., 279:23422-23430, 2004 Cited by PubMed: 15016825 DOI: 10.1074/jbc.M401648200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation