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7ZL3
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BU of 7zl3 by Molmil
Signal peptide mimicry primes Sec61 for client-selective inhibition
Descriptor: Cyclic depsipeptide signal peptide mimic, Protein transport protein Sec61 subunit alpha, Protein transport protein Sec61 subunit beta, ...
Authors:Rehan, S, Paavilainen O, V.
Deposit date:2022-04-13
Release date:2023-03-22
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Signal peptide mimicry primes Sec61 for client-selective inhibition.
Nat.Chem.Biol., 19, 2023
7ZEB
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BU of 7zeb by Molmil
Complex I from Ovis aries at pH9, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-30
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDP
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BU of 7zdp by Molmil
Complex I from Ovis aries at pH9, Open state
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDM
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BU of 7zdm by Molmil
Complex I from Ovis aries at pH5.5, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDJ
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BU of 7zdj by Molmil
Complex I from Ovis aries at pH5.5, Open state
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Acyl carrier protein, Complex I subunit B13, ...
Authors:Petrova, O, Sazanov, L.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDH
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BU of 7zdh by Molmil
Complex I from Ovis aries at pH7.4, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZD6
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BU of 7zd6 by Molmil
Complex I from Ovis aries, at pH7.4, Open state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z0G
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BU of 7z0g by Molmil
CPAP:TUBULIN:IE5 ALPHAREP COMPLEX P1 SPACE GROUP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Centromere protein J, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2022-02-22
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.487 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Z0F
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BU of 7z0f by Molmil
CPAP:S-TUBULIN:IIH5 ALPHAREP COMPLEX
Descriptor: Centromere protein J, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Campanacci, V.
Deposit date:2022-02-22
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YOB
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BU of 7yob by Molmil
Crystal structure of Aldehyde dehydrogenase 1A1 from mouse
Descriptor: Aldehyde dehydrogenase 1A1
Authors:Zhang, X.Y, Ouyang, Z.Q.
Deposit date:2022-08-01
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of aldehyde dehydrogenase 1A1 from mouse.
Biochem.Biophys.Res.Commun., 628, 2022
7WUO
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BU of 7wuo by Molmil
Unravelling structure of riboflavin synthase for designing of potential anti-bacterial drug
Descriptor: DI(HYDROXYETHYL)ETHER, Riboflavin synthase
Authors:Aris, S.N.A.M, Leow, A.T.C, Motomura, T, Jonet, M.A.
Deposit date:2022-02-09
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Unraveling the crystal structure of Leptospira kmetyi riboflavin synthase and computational analyses for potential development of new antibacterials
J.Mol.Struct., 2022
7VE3
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BU of 7ve3 by Molmil
Structure of the complex of sheep lactoperoxidase with hypoiodite at 2.70 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IODIDE ION, ...
Authors:Singh, P.K, Yamini, S, Singh, R.P, Singh, A.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2021-09-07
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence of the oxidation of iodide ion into hyper-reactive hypoiodite ion by mammalian heme lactoperoxidase.
Protein Sci., 31, 2022
7Q1F
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BU of 7q1f by Molmil
CPAP:TUBULIN:IE5 ALPHAREP COMPLEX
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CITRATE ANION, Centromere protein J, ...
Authors:Campanacci, V, Gigant, b.
Deposit date:2021-10-19
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Q1E
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BU of 7q1e by Molmil
CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX
Descriptor: Centromere protein J, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Campanacci, V, Gigant, b.
Deposit date:2021-10-19
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7ONI
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BU of 7oni by Molmil
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Descriptor: Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ...
Authors:Kostrhon, S.P, prabu, J.R, Schulman, B.A.
Deposit date:2021-05-25
Release date:2021-09-15
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
7OD1
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BU of 7od1 by Molmil
Crystal structure of RBR ubiquitin ligase ARIH2
Descriptor: E3 ubiquitin-protein ligase ARIH2, ZINC ION
Authors:Kostrhon, S.P, Prabu, J.R, Schulman, B.A.
Deposit date:2021-04-28
Release date:2021-09-15
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
7NF8
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BU of 7nf8 by Molmil
Ovine (b0,+AT-rBAT)2 hetero-tetramer, asymmetric unit, rigid-body fitted
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lee, Y, Kuehlbrandt, W.
Deposit date:2021-02-05
Release date:2022-01-19
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria.
Nat Commun, 13, 2022
7NF7
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BU of 7nf7 by Molmil
Ovine rBAT ectodomain homodimer, asymmetric unit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lee, Y, Kuehlbrandt, W.
Deposit date:2021-02-05
Release date:2022-01-19
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria.
Nat Commun, 13, 2022
7NF6
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BU of 7nf6 by Molmil
Ovine b0,+AT-rBAT heterodimer
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lee, Y, Kuehlbrandt, W.
Deposit date:2021-02-05
Release date:2022-01-19
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria.
Nat Commun, 13, 2022
7M7B
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BU of 7m7b by Molmil
SARS-CoV-2 Spike:Fab 3D11 complex focused refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 3D11 heavy chain, Antibody Fab 3D11 light chain, ...
Authors:Asarnow, D, Cheng, Y.
Deposit date:2021-03-27
Release date:2021-05-26
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7M71
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BU of 7m71 by Molmil
SARS-CoV-2 Spike:5A6 Fab complex I focused refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 5A6 Fab heavy chain, Antibody 5A6 Fab light chain, ...
Authors:Asarnow, D, Cheng, Y.
Deposit date:2021-03-26
Release date:2021-05-26
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7KQE
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BU of 7kqe by Molmil
SARS-CoV-2 spike glycoprotein:Fab 3D11 complex
Descriptor: Fab 3D11 heavy chain, Fab 3D11 light chain, Spike glycoprotein
Authors:Asarnow, D, Charles, C, Cheng, Y.
Deposit date:2020-11-15
Release date:2021-05-26
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7KQB
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BU of 7kqb by Molmil
SARS-CoV-2 spike glycoprotein:Fab 5A6 complex I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 5A6 heavy chain, Fab 5A6 light chain, ...
Authors:Asarnow, D, Charles, C, Cheng, Y.
Deposit date:2020-11-14
Release date:2021-05-26
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
7JXT
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BU of 7jxt by Molmil
Ovine COX-1 in complex with the subtype-selective derivative 2a
Descriptor: 2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ko, Y, Iaselli, M, Miciaccia, M, Friedrich, L, Schneider, G, Scilimati, A, Cingolani, G.
Deposit date:2020-08-27
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design.
Adv Sci, 8, 2021
7JN1
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BU of 7jn1 by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-08-03
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020

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