PDB: 8258 resultsInfo pagesStatus searchChemie searchBIRD

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8T13	Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 disordered Descriptor: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION Authors: Biswal, M, Lu, J, Song, J. Deposit date: 2023-06-01 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 disordered To Be Published
8T12	Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 ordered. Descriptor: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION Authors: Biswal, M, Lu, J, Song, J. Deposit date: 2023-06-01 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 ordered. To Be Published
8SZU	Structure of Kdac1-Citarinostat complex from Acinetobacter baumannii Descriptor: Citarinostat, Histone deacetylase domain-containing protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2023-05-30 Release date: 2023-09-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii . Biochemistry, 62, 2023
8SZT	Structure of Kdac1 from Acinetobacter baumannii Descriptor: CHLORIDE ION, Histone deacetylase domain-containing protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2023-05-30 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii . Biochemistry, 62, 2023
8SXU	Structure of LINE-1 ORF2p with an oligo(A) template Descriptor: LINE-1 retrotransposable element ORF2 protein, RNA (25-MER) Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8SXT	Structure of LINE-1 ORF2p with template:primer hybrid Descriptor: DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8SVF	BAP1/ASXL1 bound to the H2AK119Ub Nucleosome Descriptor: DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ... Authors: Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J. Deposit date: 2023-05-16 Release date: 2023-08-30 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Sci Adv, 9, 2023
8STV	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C, V106A) variant in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ600), a non-nucleoside inhibitor Descriptor: 1,2-ETHANEDIOL, 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile, MAGNESIUM ION, ... Authors: Hollander, K, Jorgensen, W.L, Anderson, K.S. Deposit date: 2023-05-11 Release date: 2023-11-29 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. Protein Sci., 32, 2023
8STU	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C, V106A) variant in Complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-6-fluoroindolizine-2-carbonitrile (JLJ578), a non-nucleoside inhibitor Descriptor: 8-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-6-fluoroindolizine-2-carbonitrile, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... Authors: Hollander, K, Jorgensen, W.L, Anderson, K.S. Deposit date: 2023-05-11 Release date: 2023-11-29 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. Protein Sci., 32, 2023
8STT	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C, V106A) varient in Complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)indolizine-2-carbonitrile (JLJ555), a non-nucleoside inhibitor Descriptor: 8-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}indolizine-2-carbonitrile, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... Authors: Hollander, K, Jorgensen, W.L, Anderson, K.S. Deposit date: 2023-05-11 Release date: 2023-11-29 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. Protein Sci., 32, 2023
8STS	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C, V106A) varient in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-7-fluoro-2-naphthonitrile (JLJ636), a non-nucleoside inhibitor Descriptor: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... Authors: Hollander, K, Jorgensen, W.L, Anderson, K.S. Deposit date: 2023-05-11 Release date: 2023-11-29 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.02 Å) Cite: Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. Protein Sci., 32, 2023
8SPU	Structure of ESRRB nucleosome bound OCT4 at site c Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2023-05-03 Release date: 2023-06-28 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8SPS	High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2023-05-03 Release date: 2023-06-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8SPB	Caspase-4/Pro-IL-18 complex Descriptor: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18 Authors: Pascal, D, Dong, Y, Wu, H, Jon, K. Deposit date: 2023-05-02 Release date: 2023-11-22 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature, 624, 2023
8SP1	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-05-01 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SNB	atomic model of sea urchin sperm doublet microtubule (48-nm periodicity) Descriptor: ATP6V1FNB, C20Orf85, C4orf45, ... Authors: Zeng, J, Zhang, R. Deposit date: 2023-04-26 Release date: 2023-06-28 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural specializations of the sperm tail. Cell, 2023
8SNA	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN9	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN8	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN7	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 5) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN6	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 4) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN5	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN4	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN3	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN2	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024

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