8SXU
Structure of LINE-1 ORF2p with an oligo(A) template
Summary for 8SXU
Entry DOI | 10.2210/pdb8sxu/pdb |
Related | 8SXT |
EMDB information | 40856 40858 40859 |
Descriptor | LINE-1 retrotransposable element ORF2 protein, RNA (25-MER) (2 entities in total) |
Functional Keywords | reverse transcriptase, line-1, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 157437.53 |
Authors | van Eeuwen, T.,Taylor, M.S.,Rout, M.P. (deposition date: 2023-05-24, release date: 2024-01-10, Last modification date: 2024-02-14) |
Primary citation | Baldwin, E.T.,van Eeuwen, T.,Hoyos, D.,Zalevsky, A.,Tchesnokov, E.P.,Sanchez, R.,Miller, B.D.,Di Stefano, L.H.,Ruiz, F.X.,Hancock, M.,Isik, E.,Mendez-Dorantes, C.,Walpole, T.,Nichols, C.,Wan, P.,Riento, K.,Halls-Kass, R.,Augustin, M.,Lammens, A.,Jestel, A.,Upla, P.,Xibinaku, K.,Congreve, S.,Hennink, M.,Rogala, K.B.,Schneider, A.M.,Fairman, J.E.,Christensen, S.M.,Desrosiers, B.,Bisacchi, G.S.,Saunders, O.L.,Hafeez, N.,Miao, W.,Kapeller, R.,Zaller, D.M.,Sali, A.,Weichenrieder, O.,Burns, K.H.,Gotte, M.,Rout, M.P.,Arnold, E.,Greenbaum, B.D.,Romero, D.L.,LaCava, J.,Taylor, M.S. Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626:194-206, 2024 Cited by PubMed: 38096902DOI: 10.1038/s41586-023-06947-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.66 Å) |
Structure validation
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