PDB: 34 resultsInfo pagesStatus searchChemie searchBIRD

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7ZWA	CryoEM structure of Ku heterodimer bound to DNA and PAXX Descriptor: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ... Authors: Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. Deposit date: 2022-05-19 Release date: 2023-05-31 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
7ZYG	CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF Descriptor: DNA, Non-homologous end-joining factor 1, PHOSPHATE ION, ... Authors: Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. Deposit date: 2022-05-24 Release date: 2023-06-07 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (2.68 Å) Cite: PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BHY	DNA-PK Ku80 mediated dimer bound to PAXX and XLF Descriptor: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... Authors: Hardwick, S.W, Chaplin, A.K. Deposit date: 2022-11-01 Release date: 2023-06-07 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (5.33 Å) Cite: PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BHV	DNA-PK XLF mediated dimer bound to PAXX Descriptor: DNA (24-MER), DNA (26-MER), DNA (27-MER), ... Authors: Hardwick, S.W, Chaplin, A.K. Deposit date: 2022-11-01 Release date: 2023-06-07 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (4.51 Å) Cite: PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BH3	DNA-PK Ku80 mediated dimer bound to PAXX Descriptor: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... Authors: Hardwick, S.W, Chaplin, A.K. Deposit date: 2022-10-28 Release date: 2023-06-07 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8EZB	NHEJ Long-range complex with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... Authors: Chen, S, He, Y. Deposit date: 2022-10-31 Release date: 2023-06-14 Method: ELECTRON MICROSCOPY (8.9 Å) Cite: Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. Sci Adv, 9, 2023
8EZA	NHEJ Long-range complex with PAXX Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... Authors: Chen, S, He, Y. Deposit date: 2022-10-31 Release date: 2023-06-14 Method: ELECTRON MICROSCOPY (4.39 Å) Cite: Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. Sci Adv, 9, 2023
8BOT	Cryo-EM structure of NHEJ supercomplex(trimer) Descriptor: DNA (24-MER), DNA (27-MER), DNA (28-MER), ... Authors: Hardwick, S.W, Chaplin, A.K. Deposit date: 2022-11-15 Release date: 2023-06-28 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (7.76 Å) Cite: Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ. Structure, 31, 2023
7Z6O	X-Ray studies of Ku70/80 reveal the binding site for IP6 Descriptor: DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ... Authors: Varela, P.F, Charbonnier, J.B. Deposit date: 2022-03-14 Release date: 2023-08-30 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction. Nucleic Acids Res., 51, 2023

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