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5EPM	Ceratotoxin variant in complex with specific antibody Fab fragment Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Beta-theraphotoxin-Cm1a Authors: Strop, P, Shcherbatko, A, Rossi, A. Deposit date: 2015-11-11 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain. J.Biol.Chem., 291, 2016
8FD4	Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao Descriptor: Jingzhaotoxin F7-10.36 Authors: Sharma, G, Jia, X, Chin, Y.K.Y, Mobli, M. Deposit date: 2022-12-01 Release date: 2023-11-08 Method: SOLUTION NMR Cite: Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao To Be Published
6GFT	Antinociceptive evaluation of cyriotoxin-1a, the first toxin purified from Cyriopagopus schioedtei spider venom Descriptor: cyriotoxin-1a Authors: Kurz, M. Deposit date: 2018-05-02 Release date: 2019-03-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei. Br.J.Pharmacol., 176, 2019
2WH9	Solution structure of GxTX-1E Descriptor: GUANGXITOXIN-1EGXTX-1E Authors: Lee, S.K, Jung, H.H, Lee, J.Y, Lee, C.W, Kim, J.I. Deposit date: 2009-05-02 Release date: 2010-05-26 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels. Biochemistry, 49, 2010
6MK5	Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1 Descriptor: Toxin GTx1-15 Authors: Schroeder, C.I. Deposit date: 2018-09-25 Release date: 2018-12-19 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1. ACS Chem. Biol., 14, 2019
1ZJQ	Solution structure of Jingzhaotoxin-VII Descriptor: Jingzhaotoxin-VII Authors: Liao, Z. Deposit date: 2005-04-30 Release date: 2005-05-24 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Solution structure of Jingzhaotoxin-VII TO BE PUBLISHED
1LU8	Solution structure of GsMTx-4 Descriptor: venom toxin peptide MTx4 Authors: Jung, H.J, Lee, C.W, Earm, Y.E, Kim, J.I. Deposit date: 2002-05-22 Release date: 2004-01-27 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of GsMTx-4, a peptide blocker of cation-selective stretch-activated channels To be Published
1LUP	Solution structure of a toxin (GsMTx2) from the tarantula, Grammostola spatulata, which inhibits mechanosensitive ion channels Descriptor: GsMTx2 Authors: Oswald, R.E, Suchyna, T.M, McFeeters, R, Gottlieb, P, Sachs, F. Deposit date: 2002-05-23 Release date: 2002-08-07 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of peptide toxins that block mechanosensitive ion channels J.Biol.Chem., 277, 2002
2I1T	Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels Descriptor: Jingzhaotoxin-3 Authors: Liao, Z, Peng, K, Liang, S. Deposit date: 2006-08-15 Release date: 2006-08-29 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels To be Published
5I2P	Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering) Descriptor: W7A mu-TRTX-Pre1a Toxin Authors: Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D. Deposit date: 2016-02-09 Release date: 2017-06-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a To Be Published
6V6T	Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata Descriptor: Delta-theraphotoxin-Hm1b Authors: Chin, Y.K.Y, Chow, C.Y, King, G.F. Deposit date: 2019-12-05 Release date: 2020-05-13 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy. Biochem Pharmacol, 181, 2020
1EMX	SOLUTION STRUCTURE OF HPTX2, A TOXIN FROM HETEROPODA VENATORIA SPIDER VENOM THAT BLOCKS KV4.2 POTASSIUM CHANNEL Descriptor: HETEROPODATOXIN 2 Authors: Bernard, C, Legros, C, Ferrat, G, Bishoff, U, Marquardt, A, Pongs, O, Darbon, H. Deposit date: 2000-03-20 Release date: 2001-01-24 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Sci., 9, 2000
1D1H	SOLUTION STRUCTURE OF HANATOXIN 1 Descriptor: HANATOXIN TYPE 1 Authors: Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I. Deposit date: 1999-09-16 Release date: 2000-09-20 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins. J.Mol.Biol., 297, 2000
2AAP	Solution structure of jingzhaotoxin-vii Descriptor: Jingzhaotoxin-Vii Authors: Liao, Z, Liang, S.P. Deposit date: 2005-07-14 Release date: 2005-08-02 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of jingzhaotoxin-vii TO BE PUBLISHED
5I1X	Resonance assignments and NMR structure determination of tarantula toxin, F8A mutant of beta-TRTX-Pre1a Descriptor: mu-TRTX-Pre1a toxin Authors: Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D. Deposit date: 2016-02-07 Release date: 2017-02-08 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Resonance assignments and NMR structure determination of tarantula toxin, mu-TRTX-Pre1a To Be Published
5T3M	Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7 Descriptor: Mu-theraphotoxin-Hs2a Authors: Rahnama, S, Sharma, G, Mobli, M. Deposit date: 2016-08-25 Release date: 2017-09-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant. PLoS ONE, 12, 2017
5TLR	Solution NMR structure of gHwTx-IV Descriptor: Mu-theraphotoxin-Hs2a Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2016-10-11 Release date: 2017-02-22 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochim. Biophys. Acta, 1859, 2017
2JTB	Three dimensional solution structure of hainantoxin-III by 2D 1H-NMR Descriptor: Hainantoxin-3 Authors: Zhu, Q, Liu, Z, Liang, S. Deposit date: 2007-07-25 Release date: 2007-08-21 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Three dimensional solution structure of hainantoxin-III by 2D 1H-NMR To be Published
1KOZ	SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA Descriptor: Voltage-dependent Channel Inhibitor Authors: Takeuchi, K, Park, E.J, Lee, C.W, Kim, J.I, Takahashi, H, Swartz, K.J, Shimada, I. Deposit date: 2001-12-25 Release date: 2002-08-28 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel. J.Mol.Biol., 321, 2002
5WE3	Solution NMR structure of PaurTx-3 Descriptor: Beta-theraphotoxin-Ps1a Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2017-07-06 Release date: 2017-09-13 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins. Toxins (Basel), 9, 2017
5WLX	Solution structure of kappa-theraphotoxin-Aa1a Descriptor: Kappa-theraphotoxin-Aa1a Authors: Chin, Y.K.Y, Ma, L, King, G.F. Deposit date: 2017-07-28 Release date: 2018-08-01 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochem. Pharmacol., 158, 2018
2A2V	The solution structure of Jingzhaotoxin-XI Descriptor: Jingzhaotoxin-XI Authors: Liao, Z, Liang, S.P. Deposit date: 2005-06-23 Release date: 2005-07-05 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: The solution structure of Jingzhaotoxin-XI To be published
1LA4	Solution Structure of SGTx1 Descriptor: SGTx1 Authors: Lee, C.W, Roh, S.H, Kim, S, Endoh, H, Kodera, Y, Maeda, T, Swartz, K.J, Kim, J.I. Deposit date: 2002-03-28 Release date: 2003-11-11 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating Biochemistry, 43, 2004
6AV8	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox Descriptor: U5-theraphotoxin-Hs1b 1 Authors: Gewe, M.M, Rupert, P, Strong, R.K. Deposit date: 2017-09-01 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
6BTV	Solution NMR structures for CcoTx-II Descriptor: Beta-theraphotoxin-Cm1b Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2017-12-07 Release date: 2018-05-09 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. J. Biol. Chem., 293, 2018

 

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