1L0O
| Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ... | 著者 | Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A. | 登録日 | 2002-02-12 | 公開日 | 2002-04-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell(Cambridge,Mass.), 108, 2002
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5D4C
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1L9U
| THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION | 分子名称: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | 著者 | Murakami, K.S, Masuda, S, Darst, S.A. | 登録日 | 2002-03-26 | 公開日 | 2002-05-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 2002
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4OIQ
| Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and rifampicin | 分子名称: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.624 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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4OIO
| Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription initiation | 分子名称: | 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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4G7O
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4G7Z
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1SC5
| Sigma-28(FliA)/FlgM complex | 分子名称: | RNA polymerase sigma factor FliA, anti-sigma factor FlgM | 著者 | Sorenson, M.K, Ray, S.S, Darst, S.A. | 登録日 | 2004-02-11 | 公開日 | 2004-04-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | 主引用文献 | Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation. Mol.Cell, 14, 2004
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4OIN
| Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 | 分子名称: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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1RP3
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4G7H
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1RIO
| Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ... | 著者 | Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A. | 登録日 | 2003-11-17 | 公開日 | 2004-01-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a ternary transcription activation complex. Mol.Cell, 13, 2004
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4OIR
| Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV | 分子名称: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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4Q5S
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4Q4Z
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1SMY
| Structural basis for transcription regulation by alarmone ppGpp | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-03-10 | 公開日 | 2004-05-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for transcription regulation by alarmone ppGpp Cell(Cambridge,Mass.), 117, 2004
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2CW0
| Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-15 | 公開日 | 2005-09-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation Cell(Cambridge,Mass.), 122, 2005
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2BE5
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-10-22 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12, 2005
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2A6H
| Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of transcription inhibition by antibiotic streptolydigin. Mol.Cell, 19, 2005
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2A68
| Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-01 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A69
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A6E
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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1ZYR
| Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-10 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell(Cambridge,Mass.), 122, 2005
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7MKE
| Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKJ
| Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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