PDB: 323 件ウェブページステータス検索Chemie searchBIRD

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6VJS	Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex 分子名称: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2020-01-17 公開日 2020-10-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.02 Å) 主引用文献 Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice. Acs Infect Dis., 6, 2020
6LTS	Crystal structure of Thermus thermophilus transcription initiation complex comprising a truncated sigma finger 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2020-01-23 公開日 2020-03-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVZ	Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin 分子名称: DNA (62-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVT	Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase and antibiotic Sorangicin 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVY	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with Sorangicin 分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVV	Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase 分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VW0	Mycobacterium tuberculosis RNAP S456L mutant open promoter complex 分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVS	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with antibiotic Sorangicin 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Braffman, N, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.112 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6VVX	Mycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicin 分子名称: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Boyaci, H, Chen, J, Campbell, E.A, Darst, S.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.39 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6WMT	F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.43 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMU	E. coli RNAPs70-SspA-gadA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WOX	Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... 著者 Shin, Y, Murakami, K.S. 登録日 2020-04-26 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
6WOY	Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... 著者 Shin, Y, Murakami, K.S. 登録日 2020-04-26 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
7C17	The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2020-05-02 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-06-05 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
6XH7	CueR-TAC without RNA 分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W, Yang, Y. 登録日 2020-06-18 公開日 2021-04-14 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
6XH8	CueR-transcription activation complex with RNA transcript 分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W, Yang, Y. 登録日 2020-06-18 公開日 2021-04-14 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
6XLM	Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription 分子名称: 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... 著者 Yang, Y, Liu, C, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLL	Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, Y, Liu, C, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XL9	Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Yang, Y, Liu, C, Shi, W, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLJ	Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, Y, Liu, C, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XL5	Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, Y, Liu, C, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-07-06 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7CKQ	The cryo-EM structure of B. subtilis BmrR transcription activation complex 分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2020-07-18 公開日 2020-12-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription. Nat Commun, 11, 2020

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