PDB: 457 件ウェブページステータス検索Chemie searchBIRD

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1IJF	Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ... 著者 Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. 登録日 2001-04-26 公開日 2001-05-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat.Struct.Biol., 8, 2001
5WFS	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
4MYU	Crystal structure of elongation factor G mutant(EFG) 分子名称: Elongation factor G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Liu, G, Dong, J, Gong, W, Qin, Y. 登録日 2013-09-28 公開日 2014-08-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 Crystal structure of elongation factor G mutant(EFG) To be published
6FYY	Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. 登録日 2018-03-12 公開日 2018-12-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
4AC9	CRYSTAL STRUCTURE OF TRANSLATION ELONGATION FACTOR SELB FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH GDP 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Leibundgut, M, Frick, C, Thanbichler, M, Boeck, A, Ban, N. 登録日 2011-12-14 公開日 2012-08-22 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Selenocysteine tRNA-Specific Elongation Factor Selb is a Structural Chimaera of Elongation and Initiation Factors. Embo J., 24, 2005
6O85	Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens 分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ... 著者 Nguyen, H.C, Kenner, L.R, Frost, A.S. 登録日 2019-03-08 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science, 364, 2019
4ZCL	Crystal Structure of Escherichia coli GTPase BipA/TypA Complexed with GDP 分子名称: COBALT HEXAMMINE(III), GTP-binding protein TypA/BipA, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Fan, H.T, Hahm, J, Diggs, S, Blaha, G. 登録日 2015-04-16 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural and Functional Analysis of BipA, a Regulator of Virulence in Enteropathogenic Escherichia coli. J.Biol.Chem., 290, 2015
1ZM3	Structure of the apo eEF2-ETA complex 分子名称: Elongation factor 2, exotoxin A 著者 Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. 登録日 2005-05-10 公開日 2005-05-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature, 436, 2005
1ZM2	Structure of ADP-ribosylated eEF2 in complex with catalytic fragment of ETA 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Exotoxin A 著者 Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. 登録日 2005-05-10 公開日 2005-05-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature, 436, 2005
5WE4	70S ribosome-EF-Tu wt complex with GppNHp 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Brown, Z, Frank, J. 登録日 2017-07-07 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
4V5Q	The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. 登録日 2010-12-07 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
4V5R	The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome. 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. 登録日 2010-12-07 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
4V5S	The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome. 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. 登録日 2010-12-07 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
4V5L	The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V. 登録日 2010-09-02 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Mechanism for Activation of GTP Hydrolysis on the Ribosome. Science, 330, 2010
4V8Q	Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V. 登録日 2011-12-10 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Decoding in the absence of a codon by tmRNA and SmpB in the ribosome. Science, 335, 2012
4V5P	The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. 登録日 2010-12-07 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
7O9K	Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu 分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Valentin Gese, G, Hallberg, B.M. 登録日 2021-04-16 公開日 2021-06-30 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
8G7Q	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rybak, M.Y, Gagnon, M.G. 登録日 2023-02-16 公開日 2024-03-06 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 2024
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Pena, V. 登録日 2022-01-15 公開日 2023-05-10 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
6ZMO	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-03 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6LKQ	The Structural Basis for Inhibition of Ribosomal Translocation by Viomycin 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Zhang, L, Wang, Y.H, Lancaster, L, Zhou, J, Noller, H.F. 登録日 2019-12-20 公開日 2020-05-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structural basis for inhibition of ribosomal translocation by viomycin. Proc.Natl.Acad.Sci.USA, 117, 2020
8QHC	Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX 分子名称: E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Sharma, R, Adams, M, Bhogaraju, S. 登録日 2023-09-07 公開日 2023-10-11 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for the toxicity of Legionella pneumophila effector SidH. Nat Commun, 14, 2023
5H7L	Complex of Elongation factor 2-50S ribosomal protein L12 分子名称: 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER 著者 Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. 登録日 2016-11-18 公開日 2018-02-21 最終更新日 2018-05-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Nucleic Acids Res., 46, 2018
8Q7N	cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. 登録日 2023-08-16 公開日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes To Be Published

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