3H3F
| Rabbit muscle L-lactate dehydrogenase in complex with NADH and oxamate | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, L-lactate dehydrogenase A chain, ... | 著者 | Bujacz, A, Bujacz, G, Swiderek, K, Paneth, P. | 登録日 | 2009-04-16 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Modeling of isotope effects on binding oxamate to lactic dehydrogenase J.Phys.Chem.B, 113, 2009
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7QOZ
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3HHP
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6SBU
| X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3) | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid, L-lactate dehydrogenase A chain | 著者 | Friberg, A, Puetter, V, Nguyen, D, Rehwinkel, H. | 登録日 | 2019-07-22 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A. Acs Omega, 5, 2020
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6SBV
| X-ray Structure of Human LDH-A with an Allosteric Inhibitor (Compound 7) | 分子名称: | L-lactate dehydrogenase A chain, ~{N}-[3-[(7-nitrodibenzofuran-2-yl)sulfonylamino]phenyl]-1-oxidanyl-cyclopropane-1-carboxamide | 著者 | Friberg, A, Puetter, V, Nguyen, D, Rehwinkel, H. | 登録日 | 2019-07-22 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A. Acs Omega, 5, 2020
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7RM9
| Human Malate Dehydrogenase I (MDHI) | 分子名称: | MALONATE ION, Malate dehydrogenase, cytoplasmic | 著者 | McCue, W, Finzel, B.C. | 登録日 | 2021-07-27 | 公開日 | 2022-01-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Characterization of the Human Cytosolic Malate Dehydrogenase I. Acs Omega, 7, 2022
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7RRL
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5HTO
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5HS4
| Plasmdoium Vivax Lactate dehydrogenase | 分子名称: | L-lactate dehydrogenase | 著者 | Choi, S.J, Ban, C. | 登録日 | 2016-01-25 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.339 Å) | 主引用文献 | Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
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5HRU
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8FW6
| Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336 | 分子名称: | (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Lowther, W.T, Gumpena, R. | 登録日 | 2023-01-20 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Human Lactate Dehydrogenase A in complex with inhibitor CHK-336 To Be Published
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8GH2
| Structure of Trypanosoma (MDH)4-(Pex5)2, close conformation | 分子名称: | Peroxisome targeting signal 1 receptor, malate dehydrogenase | 著者 | Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. | 登録日 | 2023-03-09 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structure of Trypanosoma (MDH)4-(Pex5)2, close conformation To Be Published
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8GGH
| Structure of Trypanosoma (MDH)4-PEX5, distal conformation | 分子名称: | Peroxisome targeting signal 1 receptor, malate dehydrogenase | 著者 | Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. | 登録日 | 2023-03-08 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structure of Trypanosoma (MDH)4-PEX5, distal conformation To Be Published
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8GH3
| Structure of Trypanosoma (MDH)4-(Pex5)2, distal conformation | 分子名称: | Peroxisome targeting signal 1 receptor, malate dehydrogenase | 著者 | Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. | 登録日 | 2023-03-09 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structure of Trypanosoma (MDH)4-(Pex5)2, distal conformation To Be Published
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8GGD
| Structure of Trypanosoma (MDH)4-Pex5, close conformation | 分子名称: | Peroxisome targeting signal 1 receptor, malate dehydrogenase | 著者 | Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. | 登録日 | 2023-03-08 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structure of Trypanosoma (MDH)4-Pex5, close conformation To Be Published
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5IXY
| Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one | 分子名称: | (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Chen, Z, Eigenbrot, C. | 登録日 | 2016-03-23 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. Acs Med.Chem.Lett., 7, 2016
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5IXS
| Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 9: (6R)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(3-hydroxyphenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one | 分子名称: | (6R)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(3-hydroxyphenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Ultsch, M, Eigenbrot, C. | 登録日 | 2016-03-23 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. Acs Med.Chem.Lett., 7, 2016
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3CZM
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8GI0
| Structure of Trypanosoma docking complex | 分子名称: | Peroxisomal membrane protein PEX14, Peroxisome targeting signal 1 receptor, malate dehydrogenase | 著者 | Sonani, R.R, Artur, B, Jemiola-Rzeminska, M, Lipinski, O, Patel, S.N, Sood, T, Dubin, G. | 登録日 | 2023-03-13 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of Trypanosoma docking complex To Be Published
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3D5T
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3D0O
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3D4P
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5K0Z
| Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state | 分子名称: | L-lactate dehydrogenase B chain | 著者 | Merk, A, Bartesaghi, A, Banerjee, S, Falconieri, V, Rao, P, Earl, L, Milne, J, Subramaniam, S. | 登録日 | 2016-05-17 | 公開日 | 2016-06-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery. Cell, 165, 2016
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3DL2
| Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A | 分子名称: | PHOSPHATE ION, SODIUM ION, Ubiquitin-conjugating enzyme E2 variant 3 | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Bountra, C, Wolkstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-06-26 | 公開日 | 2008-07-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Investigation Into the L-Lactate Dehydrogenase Domain of Human Ubiquitin-Conjugating Enzyme E2-Like Isoform A. To be Published
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3FI9
| Crystal structure of malate dehydrogenase from Porphyromonas gingivalis | 分子名称: | Malate dehydrogenase | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Miller, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-12-11 | 公開日 | 2008-12-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of malate dehydrogenase from Porphyromonas gingivalis To be Published
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