6LEM
 
 | | Structure of E. coli beta-glucuronidase complex with C6-nonyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-nonyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.188 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LDD
 | | Structure of Bifidobacterium dentium beta-glucuronidase complexed with C6-propyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, LacZ1 Beta-galactosidase | | 著者 | Lin, H.-Y, Hsieh, T.-J, Lin, C.-H. | | 登録日 | 2019-11-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LEG
 | | Structure of E. coli beta-glucuronidase complex with uronic isofagomine | | 分子名称: | (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LEJ
 | | Structure of E. coli beta-glucuronidase complex with C6-propyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.617 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LEL
 | | Structure of E. coli beta-glucuronidase complex with C6-hexyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-hexyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LDC
 | | Structure of Bifidobacterium dentium beta-glucuronidase complexed with C6-nonyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-nonyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, LacZ1 Beta-galactosidase | | 著者 | Lin, H.-Y, Hsieh, T.-J, Lin, C.-H. | | 登録日 | 2019-11-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.181 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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7CWI
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7CWD
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6ZJP
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6ZJU
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with saccharose | | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6ZJX
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant D207A in complex with saccharose | | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6ZJQ
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E517Q in complex with galactose | | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6ZJW
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6ZJT
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with lactulose | | 分子名称: | ACETATE ION, Beta-galactosidase, SODIUM ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6ZJV
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6ZJR
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E517Q in complex with lactulose | | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6ZJS
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with galactose | | 分子名称: | (2S)-2-hydroxybutanedioic acid, ACETATE ION, Beta-galactosidase, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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6XXW
 | | Structure of beta-D-Glucuronidase for Dictyoglomus thermophilum. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucuronidase, ... | | 著者 | Lafite, P, Daniellou, R. | | 登録日 | 2020-01-28 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Thioglycoligation of aromatic thiols using a natural glucuronide donor.
Org.Biomol.Chem., 18, 2020
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6KUZ
 | | E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01 | | 分子名称: | 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | | 著者 | Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J. | | 登録日 | 2019-09-03 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.
Chem Sci, 11, 2020
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6X1Q
 | | 1.8 Angstrom resolution structure of b-galactosidase with a 200 kV cryoARM electron microscope | | 分子名称: | Beta-galactosidase, MAGNESIUM ION, SODIUM ION | | 著者 | Merk, A, Fukumura, T, Zhu, X, Darling, J, Grisshammer, R, Ognjenovic, J, Subramaniam, S. | | 登録日 | 2020-05-19 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (1.8 Å) | | 主引用文献 | 1.8 angstrom resolution structure of beta-galactosidase with a 200 kV CRYO ARM electron microscope.
Iucrj, 7, 2020
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6JZ2
 | | b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution | | 分子名称: | (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | 著者 | Dashnyam, P, Lin, H.Y. | | 登録日 | 2019-04-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
J.Med.Chem., 63, 2020
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6JZ7
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6JZ6
 | | b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, Beta-glucuronidase | | 著者 | Dashnyam, P, Lin, H.Y. | | 登録日 | 2019-04-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.605 Å) | | 主引用文献 | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
J.Med.Chem., 63, 2020
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6JZ5
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6JZ8
 | | b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone | | 分子名称: | (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, Beta-glucuronidase | | 著者 | Dashnyam, P, Lin, H.Y. | | 登録日 | 2019-04-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.583 Å) | | 主引用文献 | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
J.Med.Chem., 63, 2020
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