6JZ2

b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution

Summary for 6JZ2

• Entry DOI: 10.2210/pdb6jz2/pdb
• Descriptor: Beta-glucuronidase, (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total)
• Functional Keywords: b-glucuronidase, hydrolase
• Biological source: Ruminococcus gnavus
• Total number of polymer chains: 2
• Total formula weight: 146450.79

Authors

Dashnyam, P.,Lin, H.Y. (deposition date: 2019-04-30, release date: 2020-06-10, Last modification date: 2023-11-22)

• Primary citation: Dashnyam, P.,Lin, H.Y.,Chen, C.Y.,Gao, S.,Yeh, L.F.,Hsieh, W.C.,Tu, Z.,Lin, C.H.; Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.; J.Med.Chem., 63:4617-4627, 2020; PubMed: 32105467; DOI: 10.1021/acs.jmedchem.9b01918

Experimental method

X-RAY DIFFRACTION (1.29 Å)