6JZ2
b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0004566 | molecular_function | beta-glucuronidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0004566 | molecular_function | beta-glucuronidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue SJ5 A 701 |
| Chain | Residue |
| A | ASP167 |
| A | LYS576 |
| A | HOH930 |
| A | HOH1059 |
| A | HOH1143 |
| A | HIS335 |
| A | GLU418 |
| A | TYR474 |
| A | TYR478 |
| A | GLU512 |
| A | TRP557 |
| A | ARG570 |
| A | ASN574 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MRD A 702 |
| Chain | Residue |
| A | ARG98 |
| A | GLY99 |
| A | THR100 |
| A | LYS137 |
| A | ASN139 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue SJ5 B 701 |
| Chain | Residue |
| B | ASP167 |
| B | HIS335 |
| B | GLU418 |
| B | TYR474 |
| B | TYR478 |
| B | GLU512 |
| B | TRP557 |
| B | ARG570 |
| B | ASN574 |
| B | LYS576 |
| B | HOH857 |
| B | HOH971 |
| B | HOH1070 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MRD B 702 |
| Chain | Residue |
| B | TYR425 |
| B | ALA426 |
| B | PHE430 |
| B | MRD704 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MPD B 703 |
| Chain | Residue |
| B | GLY99 |
| B | THR100 |
| B | HIS111 |
| B | LYS137 |
| B | ASN139 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MRD B 704 |
| Chain | Residue |
| B | GLU144 |
| B | MET362 |
| B | LEU389 |
| B | MRD702 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue MPD B 705 |
| Chain | Residue |
| B | MET569 |
| B | HOH857 |
| B | HOH919 |
Functional Information from PROSITE/UniProt
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NcFRTSHYPyaeeWYqfaDeeGFLII |
| Chain | Residue | Details |
| A | ASN329-ILE354 |
