6JZ2
b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
A | 0004565 | molecular_function | beta-galactosidase activity |
A | 0004566 | molecular_function | beta-glucuronidase activity |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0030246 | molecular_function | carbohydrate binding |
B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
B | 0004565 | molecular_function | beta-galactosidase activity |
B | 0004566 | molecular_function | beta-glucuronidase activity |
B | 0005975 | biological_process | carbohydrate metabolic process |
B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
B | 0030246 | molecular_function | carbohydrate binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue SJ5 A 701 |
Chain | Residue |
A | ASP167 |
A | LYS576 |
A | HOH930 |
A | HOH1059 |
A | HOH1143 |
A | HIS335 |
A | GLU418 |
A | TYR474 |
A | TYR478 |
A | GLU512 |
A | TRP557 |
A | ARG570 |
A | ASN574 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue MRD A 702 |
Chain | Residue |
A | ARG98 |
A | GLY99 |
A | THR100 |
A | LYS137 |
A | ASN139 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue SJ5 B 701 |
Chain | Residue |
B | ASP167 |
B | HIS335 |
B | GLU418 |
B | TYR474 |
B | TYR478 |
B | GLU512 |
B | TRP557 |
B | ARG570 |
B | ASN574 |
B | LYS576 |
B | HOH857 |
B | HOH971 |
B | HOH1070 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue MRD B 702 |
Chain | Residue |
B | TYR425 |
B | ALA426 |
B | PHE430 |
B | MRD704 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue MPD B 703 |
Chain | Residue |
B | GLY99 |
B | THR100 |
B | HIS111 |
B | LYS137 |
B | ASN139 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue MRD B 704 |
Chain | Residue |
B | GLU144 |
B | MET362 |
B | LEU389 |
B | MRD702 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue MPD B 705 |
Chain | Residue |
B | MET569 |
B | HOH857 |
B | HOH919 |
Functional Information from PROSITE/UniProt
site_id | PS00719 |
Number of Residues | 26 |
Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NcFRTSHYPyaeeWYqfaDeeGFLII |
Chain | Residue | Details |
A | ASN329-ILE354 |