6JZ2

b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-glucuronidase	polymer	627	72768.8	2	UniProt (Q6W7J7) Pfam (PF02837) Pfam (PF00703) Pfam (PF02836)	Ruminococcus gnavus
2	C, E (A, B)	(3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid	non-polymer		161.2	2	Chemie (SJ5)
3	D, F, H (A, B)	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	3	Chemie (MRD)
4	G, I (B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
5	J, K (A, B)	water	water		18.0	1111	Chemie (HOH)

Sequence modifications

A, B: 1 - 603 (UniProt: Q6W7J7)

PDB	External Database	Details
Met -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	145537.6
Non-Polymers*	Number of molecules	7
	Total formula weight	913.2
All*	Total formula weight	146450.8

*Water molecules are not included.