PDB: 61 件ウェブページステータス検索Chemie searchBIRD

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2MUX	SUMO2 non-covalently interacts with USP25 and downregulates its activity 分子名称: Ubiquitin carboxyl-terminal hydrolase 25 著者 Shi, L, Zhang, N, Wen, Y. 登録日 2014-09-18 公開日 2016-04-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 SUMO2 non-covalently interacts with USP25 and downregulates its activity To be Published
1YX4	Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition 分子名称: 26S proteasome non-ATPase regulatory subunit 4 著者 Wang, Q, Young, P, Walters, K.J. 登録日 2005-02-19 公開日 2005-04-19 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition J.Mol.Biol., 348, 2005
2KLZ	Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin 分子名称: Ataxin-3 著者 Zhou, C, Song, A, Lin, D, Hu, H. 登録日 2009-07-12 公開日 2010-07-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin To be Published
1O06	Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM) 分子名称: Vacuolar protein sorting-associated protein VPS27, ZINC ION 著者 Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P. 登録日 2003-02-20 公開日 2003-07-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure and ubiquitin binding of the ubiquitin-interacting motif. J.Biol.Chem., 278, 2003
1P9C	NMR solution structure of the C-terminal ubiquitin-interacting motif of the proteasome subunit S5a 分子名称: 26S proteasome non-ATPase regulatory subunit 4 著者 Mueller, T.D, Feigon, J. 登録日 2003-05-10 公開日 2003-10-07 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structural determinants for the binding of ubiquitin-like domains to the proteasome. Embo J., 22, 2003
1Q0V	Solution Structure of Tandem UIMs of Vps27 分子名称: hydrophilic protein; has cysteine rich putative zinc finger essential for function; Vps27p 著者 Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I. 登録日 2003-07-17 公開日 2003-12-23 最終更新日 2022-12-21 実験手法 SOLUTION NMR 主引用文献 Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation. Embo J., 22, 2003
5O71	Crystal structure of human USP25 分子名称: Ubiquitin carboxyl-terminal hydrolase 25 著者 Reverter, D, Liu, B. 登録日 2017-06-07 公開日 2018-06-20 最終更新日 2019-04-17 実験手法 X-RAY DIFFRACTION (3.283 Å) 主引用文献 A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25. Nat Commun, 9, 2018
8CVT	Human 19S-20S proteasome, state SD2 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... 著者 Zhao, J. 登録日 2022-05-18 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
1UEL	Solution structure of ubiquitin-like domain of hHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5a 分子名称: 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog B 著者 Fujiwara, K, Tenno, T, Jee, J.G, Sugasawa, K, Ohki, I, Kojima, C, Tochio, H, Hiroaki, H, Hanaoka, H, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-05-19 公開日 2004-02-10 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B J.Biol.Chem., 279, 2004
6WJD	SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A 分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... 著者 Chen, X, Walters, K.J. 登録日 2020-04-13 公開日 2020-08-05 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
6MSD	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome 分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... 著者 Mao, Y.D. 登録日 2018-10-16 公開日 2018-12-05 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6NJG	Ubiquitin Variant in Complex with Ubiquitin Interacting Motif 分子名称: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27 著者 Manczyk, N, Sicheri, F. 登録日 2019-01-03 公開日 2019-03-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif. Protein Sci., 28, 2019
5GJQ	Structure of the human 26S proteasome bound to USP14-UbAl 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. 登録日 2016-07-01 公開日 2016-08-17 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
5GJR	An atomic structure of the human 26S proteasome 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. 登録日 2016-07-01 公開日 2016-09-07 最終更新日 2019-10-09 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
5L4K	The human 26S proteasome lid 分子名称: 26S proteasome complex subunit DSS1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... 著者 Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F. 登録日 2016-05-25 公開日 2016-09-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure of the human 26S proteasome at a resolution of 3.9 angstrom. Proc.Natl.Acad.Sci.USA, 113, 2016
1YX6	Solution Structure of S5a UIM-2/Ubiquitin Complex 分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin 著者 Wang, Q, Young, P, Walters, K.J. 登録日 2005-02-19 公開日 2005-04-19 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition J.Mol.Biol., 348, 2005
1YX5	Solution Structure of S5a UIM-1/Ubiquitin Complex 分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin 著者 Wang, Q, Young, P, Walters, K.J. 登録日 2005-02-19 公開日 2005-04-19 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition J.Mol.Biol., 348, 2005
5LN3	The human 26S Proteasome at 6.8 Ang. 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P. 登録日 2016-08-03 公開日 2017-03-22 最終更新日 2017-05-24 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol. Cell Proteomics, 16, 2017
5M32	Human 26S proteasome in complex with Oprozomib 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. 登録日 2016-10-14 公開日 2017-07-05 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nat Commun, 8, 2017
5IXF	Solution structure of the STAM2 SH3 with AMSH derived peptide complex 分子名称: STAM-binding protein, Signal transducing adapter molecule 2 著者 Hologne, M, Cantrelle, F.X, Trivelli, X, Walker, O. 登録日 2016-03-23 公開日 2016-12-07 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin. J.Mol.Biol., 428, 2016
2KDF	NMR structure of minor S5a (196-306):K48 linked diubiquitin species 分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin 著者 Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. 登録日 2009-01-06 公開日 2009-09-01 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
2KDE	NMR structure of major S5a (196-306):K48 linked diubiquitin species 分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin 著者 Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. 登録日 2009-01-06 公開日 2009-09-01 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
6EPC	Ground state 26S proteasome (GS2) 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... 著者 Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (12.3 Å) 主引用文献 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPD	Substrate processing state 26S proteasome (SPS1) 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... 著者 Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (15.4 Å) 主引用文献 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPF	Ground state 26S proteasome (GS1) 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... 著者 Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (11.8 Å) 主引用文献 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018

 

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