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8Q7I
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PCNA from Chaetomium thermophilum in complex with Fen1 peptide
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.S, Wolford, C.B, MacNeill, S.A.
Deposit date:2023-08-16
Release date:2023-12-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA.
Front Mol Biosci, 10, 2023
2ZVK
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BU of 2zvk by Molmil
Crystal structure of PCNA in complex with DNA polymerase eta fragment
Descriptor: DNA polymerase eta, Proliferating cell nuclear antigen
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
2ZVM
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Crystal structure of PCNA in complex with DNA polymerase iota fragment
Descriptor: DNA polymerase iota, Proliferating cell nuclear antigen
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
2ZVW
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Crystal structure of Proliferating cell nuclear antigen 2 and Short peptide from human P21
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen 2, SULFATE ION
Authors:Strzalka, W, Oyama, T, Tori, K, Morikawa, K.
Deposit date:2008-11-21
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
2ZVV
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Crystal structure of Proliferating cellular nuclear antigen 1 and Short peptide from human P21
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cellular nuclear antigen 1, SULFATE ION
Authors:Strzalka, W, Oyama, T, Tori, K, Morikawa, K.
Deposit date:2008-11-21
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
2ZVL
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Crystal structure of PCNA in complex with DNA polymerase kappa fragment
Descriptor: DNA polymerase kappa, Proliferating cell nuclear antigen, SULFATE ION, ...
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
1RWZ
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Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) from A. fulgidus
Descriptor: DNA polymerase sliding clamp
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-17
Release date:2004-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RXM
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C-terminal region of FEN-1 bound to A. fulgidus PCNA
Descriptor: DNA polymerase sliding clamp, consensus FEN-1 peptide
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
3F1W
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Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Ramaswamy, S, Washington, M.T.
Deposit date:2008-10-28
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis.
Biochemistry, 47, 2008
1RXZ
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C-terminal region of A. fulgidus FEN-1 complexed with A. fulgidus PCNA
Descriptor: DNA polymerase sliding clamp, Flap structure-specific endonuclease
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
3FDS
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BU of 3fds by Molmil
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ...
Authors:Ling, H.
Deposit date:2008-11-26
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA
Mol.Microbiol., 71, 2009
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
3LX2
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BU of 3lx2 by Molmil
Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
Descriptor: DNA polymerase sliding clamp 2, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3LX1
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BU of 3lx1 by Molmil
Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535
Descriptor: DNA polymerase sliding clamp 1, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
Descriptor: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
Authors:Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
Deposit date:2018-10-11
Release date:2019-01-23
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
5YD8
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BU of 5yd8 by Molmil
Crystal structure of human PCNA in complex with APIM of human ZRANB3
Descriptor: Proliferating cell nuclear antigen, ZRANB3
Authors:Hashimoto, H, Tagata, R.
Deposit date:2017-09-12
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction.
Acta Crystallogr.,Sect.F, 74, 2018
8F5Q
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BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
Descriptor: F-box DNA helicase 1, Proliferating cell nuclear antigen
Authors:Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
Deposit date:2022-11-15
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
5YCO
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BU of 5yco by Molmil
Complex structure of PCNA with UHRF2
Descriptor: E3 ubiquitin-protein ligase UHRF2, GLYCEROL, Proliferating cell nuclear antigen, ...
Authors:Wu, M, Chen, W, Hang, T, Wang, C, Zhang, X, Zang, J.
Deposit date:2017-09-07
Release date:2017-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
6J0J
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BU of 6j0j by Molmil
Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proliferating cell nuclear antigen
Authors:Iqbal, N, Sharma, S, Singh, T.P.
Deposit date:2018-12-24
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285
To Be Published
3TBL
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BU of 3tbl by Molmil
Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki Fragment Maturation
Descriptor: Proliferating cell nuclear antigen, Ubiquitin
Authors:Zhang, Z, Lee, M, Lee, E, Zhang, S.
Deposit date:2011-08-07
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation.
Cell Cycle, 11, 2012
6K2M
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BU of 6k2m by Molmil
Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
Descriptor: ARGININE, Proliferating cell nuclear antigen
Authors:Viswanathan, V, Iqbal, N, Sharma, S, Singh, T.P.
Deposit date:2019-05-15
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
To Be Published
5ZUT
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BU of 5zut by Molmil
Crystal Structure of Yeast PCNA in Complex with N24 Peptide
Descriptor: N24, Proliferating cell nuclear antigen
Authors:Cheng, X.Y, Kuang, X.L, Zhou, Y, Xia, X.M, SU, Z.D.
Deposit date:2018-05-08
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal Structure of Yeast PCNA in Complex with N24 Peptide
To Be Published
8GL9
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BU of 8gl9 by Molmil
Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE
Descriptor: CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
Authors:Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J.
Deposit date:2023-03-21
Release date:2023-07-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
8GLA
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BU of 8gla by Molmil
Co-crystal structure of caPCNA bound to the AOH1996 derivative, AOH1996-1LE
Descriptor: CHLORIDE ION, N-[2-(3-methoxyphenoxy)phenyl]-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
Authors:Jossart, J, Perry, J.J.
Deposit date:2023-03-21
Release date:2023-07-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
2HII
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BU of 2hii by Molmil
heterotrimeric PCNA sliding clamp
Descriptor: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
Authors:Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
Deposit date:2006-06-29
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006

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