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8I9J
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The PKR and E3L complex
分子名称: Interferon-induced, double-stranded RNA-activated protein kinase, RNA-binding protein E3
著者Han, C.W, Kim, H.J.
登録日2023-02-07
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (6.39 Å)
主引用文献Structural study of novel vaccinia virus E3L and dsRNA-dependent protein kinase complex.
Biochem.Biophys.Res.Commun., 665, 2023
8GBD
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Homo sapiens Zalpha mutant - P193A
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Langeberg, C.J, Vogeli, B, Nichols, P.J, Henen, M, Vicens, Q.
登録日2023-02-25
公開日2023-03-22
最終更新日2023-03-29
実験手法SOLUTION NMR
主引用文献Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
8GBC
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Homo sapiens Zalpha mutant - N173S
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Langeberg, C.J, Nichols, P.J, Henen, M, Vicens, Q, Vogeli, B.
登録日2023-02-25
公開日2023-03-22
最終更新日2023-03-29
実験手法SOLUTION NMR
主引用文献Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
7C0J
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Crystal structure of chimeric mutant of GH5 in complex with Z-DNA
分子名称: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Histone H5,Double-stranded RNA-specific adenosine deaminase
著者Choi, H.J, Park, C.H.
登録日2020-05-01
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Dual conformational recognition by Z-DNA binding protein is important for the B-Z transition process.
Nucleic Acids Res., 48, 2020
7C0I
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Crystal structure of chimeric mutant of E3L in complex with Z-DNA
分子名称: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Double-stranded RNA-binding protein,Double-stranded RNA-specific adenosine deaminase, SULFATE ION
著者Choi, H.J, Park, C.H, Kim, J.S.
登録日2020-05-01
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dual conformational recognition by Z-DNA binding protein is important for the B-Z transition process.
Nucleic Acids Res., 48, 2020
5ZU1
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Crystal Structure of BZ junction in diverse sequence
分子名称: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*AP*GP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*TP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase
著者Kim, K.K, Kim, D.
登録日2018-05-05
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
5ZUO
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Crystal Structure of BZ junction in diverse sequence
分子名称: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase
著者Kim, K.K, Kim, D.
登録日2018-05-08
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
5ZUP
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Crystal Structure of BZ junction in diverse sequence
分子名称: (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3'), (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*AP*AP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase
著者Kim, K.K, Kim, D.
登録日2018-05-08
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
5J6X
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Crystal structure of the apo-Zalpha of Zebrafish PKZ
分子名称: Z-DNA binding protein kinase
著者Subramani, V.K, Kim, D, Kim, K.K.
登録日2016-04-05
公開日2016-09-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structural and functional studies of a large winged Z-DNA-binding domain of Danio rerio protein kinase PKZ
Febs Lett., 590, 2016
2RVC
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Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase
分子名称: Interferon-inducible and double-stranded-dependent eIF-2kinase
著者Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J.
登録日2015-07-08
公開日2016-02-03
最終更新日2017-06-07
実験手法SOLUTION NMR
主引用文献Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition.
Nucleic Acids Res., 44, 2016
4WCG
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The binding mode of Cyprinid Herpesvirus3 ORF112-Zalpha to Z-DNA
分子名称: DNA (5'-D(P*CP*GP*CP*GP*CP*G)-3'), ORF112, SULFATE ION
著者Kus, K, Athanasiadis, A.
登録日2014-09-04
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Structure of the Cyprinid herpesvirus 3 ORF112-Z alpha Z-DNA Complex Reveals a Mechanism of Nucleic Acids Recognition Conserved with E3L, a Poxvirus Inhibitor of Interferon Response.
J.Biol.Chem., 290, 2015
4LB6
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Crystal structure of PKZ Zalpha in complex with ds(CG)6 (tetragonal form)
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', Protein kinase containing Z-DNA binding domains
著者De Rosa, M, Zacarias, S, Athanasiadis, A.
登録日2013-06-20
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
4LB5
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Crystal structure of PKZ Zalpha in complex with ds(CG)6 (hexagonal form)
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', ACETATE ION, Protein kinase containing Z-DNA binding domains
著者De Rosa, M, Zacarias, S, Athanasiadis, A.
登録日2013-06-20
公開日2013-09-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
4HOB
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The crystal structure of the Zalpha domain from Cyprinid Herpes virus 3
分子名称: Putative uncharacterized protein, SULFATE ION
著者Tome, A.R, Kus, K, de Rosa, M, Paulo, L.M, Figueiredo, D, Athanasiadis, A.
登録日2012-10-22
公開日2013-09-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of a poxvirus-like zalpha domain from cyprinid herpesvirus 3
J.Virol., 87, 2013
4KMF
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BU of 4kmf by Molmil
Crystal structure of Zalpha domain from Carassius auratus PKZ in complex with Z-DNA
分子名称: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Interferon-inducible and double-stranded-dependent eIF-2kinase, MANGANESE (II) ION
著者Kim, D, Kim, K.K.
登録日2013-05-08
公開日2013-07-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ).
Nucleic Acids Res., 42, 2014
2LNB
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Solution NMR structure of N-terminal domain (6-74) of human ZBP1 protein, Northeast Structural Genomics Consortium Target HR8174A.
分子名称: Z-DNA-binding protein 1
著者Yang, Y, Ramelot, T.A, Hamilton, K, Kohan, E, Wang, D, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2011-12-20
公開日2012-01-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution NMR structure of N-terminal domain (6-74) of human ZBP1 protein, Northeast Structural Genomics Consortium Target HR8174A
To be Published
2L54
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Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A)
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Zhao, J, Pervushin, K, Feng, S, Droge, P.
登録日2010-10-24
公開日2011-01-12
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Alternate rRNA secondary structures as regulators of translation
Nat.Struct.Mol.Biol., 18, 2011
3IRQ
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Crystal structure of a Z-Z junction
分子名称: DNA (5'-D(*AP*CP*CP*GP*CP*GP*CP*GP*AP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*TP*CP*GP*CP*GP*CP*G)-3'), Double-stranded RNA-specific adenosine deaminase
著者Athanasiadis, A, de Rosa, M.
登録日2009-08-24
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a junction between two Z-DNA helices.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IRR
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Crystal Structure of a Z-Z junction (with HEPES intercalating)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*A*CP*CP*GP*CP*GP*CP*GP*AP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*G*TP*CP*GP*CP*GP*CP*GP*TP*CP*GP*CP*GP*CP*G)-3'), ...
著者Athanasiadis, A, de Rosa, M.
登録日2009-08-24
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of a junction between two Z-DNA helices.
Proc.Natl.Acad.Sci.USA, 107, 2010
3F21
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Crystal structure of Zalpha in complex with d(CACGTG)
分子名称: DNA (5'-D(*DTP*DCP*DAP*DCP*DGP*DTP*DG)-3'), Double-stranded RNA-specific adenosine deaminase
著者Ha, S.C, Choi, J, Kim, K.K.
登録日2008-10-28
公開日2008-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Nucleic Acids Res., 37, 2009
3F23
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Crystal structure of Zalpha in complex with d(CGGCCG)
分子名称: DNA (5'-D(*DTP*DCP*DGP*DGP*DCP*DCP*DG)-3'), Double-stranded RNA-specific adenosine deaminase
著者Ha, S.C, Choi, J, Kim, K.K.
登録日2008-10-28
公開日2008-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Nucleic Acids Res., 37, 2009
3F22
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Crystal structure of Zalpha in complex with d(CGTACG)
分子名称: DNA (5'-D(*DTP*DCP*DGP*DTP*DAP*DCP*DG)-3'), Double-stranded RNA-specific adenosine deaminase
著者Ha, S.C, Choi, J, Kim, K.K.
登録日2008-10-28
公開日2008-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Nucleic Acids Res., 37, 2009
2GXB
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BU of 2gxb by Molmil
Crystal Structure of The Za Domain bound to Z-RNA
分子名称: 5'-R(P*(DU)P*CP*GP*CP*GP*CP*G)-3', Double-stranded RNA-specific adenosine deaminase, SODIUM ION
著者Athanasiadis, A, Placido, D, Rich, A.
登録日2006-05-08
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1.
Structure, 15, 2007
2HEO
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General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
著者Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P.
登録日2006-06-21
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
2ACJ
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Crystal structure of the B/Z junction containing DNA bound to Z-DNA binding proteins
分子名称: 5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*GP*GP*CP*GP*CP*GP*CP*G)-3', 5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*AP*TP*AP*AP*AP*CP*C)-3', Double-stranded RNA-specific adenosine deaminase
著者Ha, S.C, Lowenhaupt, K, Rich, A, Kim, Y.-G, Kim, K.K.
登録日2005-07-19
公開日2005-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases.
Nature, 437, 2005

 

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