4WCG
The binding mode of Cyprinid Herpesvirus3 ORF112-Zalpha to Z-DNA
Summary for 4WCG
Entry DOI | 10.2210/pdb4wcg/pdb |
Related | 4HOB |
Descriptor | ORF112, DNA (5'-D(P*CP*GP*CP*GP*CP*G)-3'), SULFATE ION, ... (4 entities in total) |
Functional Keywords | zalpha, z-dna, innate immunity, herpes virus, dna binding protein |
Biological source | Cyprinid herpesvirus 3 More |
Total number of polymer chains | 4 |
Total formula weight | 33584.26 |
Authors | Kus, K.,Athanasiadis, A. (deposition date: 2014-09-04, release date: 2015-11-18, Last modification date: 2024-01-10) |
Primary citation | Kus, K.,Rakus, K.,Boutier, M.,Tsigkri, T.,Gabriel, L.,Vanderplasschen, A.,Athanasiadis, A. The Structure of the Cyprinid herpesvirus 3 ORF112-Z alpha Z-DNA Complex Reveals a Mechanism of Nucleic Acids Recognition Conserved with E3L, a Poxvirus Inhibitor of Interferon Response. J.Biol.Chem., 290:30713-30725, 2015 Cited by PubMed: 26559969DOI: 10.1074/jbc.M115.679407 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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