4LB6

Crystal structure of PKZ Zalpha in complex with ds(CG)6 (tetragonal form)

Summary for 4LB6

• Entry DOI: 10.2210/pdb4lb6/pdb
• Related: 4LB5
• Descriptor: Protein kinase containing Z-DNA binding domains, 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3' (3 entities in total)
• Functional Keywords: whth, zalpha, zbd, kinase, innate immunity, z-dna, z-rna, eif2a, transferase-dna complex, transferase/dna
• Biological source: Danio rerio (leopard danio,zebra danio,zebra fish); More
• Total number of polymer chains: 2
• Total formula weight: 12420.14

Authors

De Rosa, M.,Zacarias, S.,Athanasiadis, A. (deposition date: 2013-06-20, release date: 2013-09-18, Last modification date: 2023-09-20)

• Primary citation: de Rosa, M.,Zacarias, S.,Athanasiadis, A.; Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.; Nucleic Acids Res., 41:9924-9933, 2013; PubMed: 23975196; DOI: 10.1093/nar/gkt743

Experimental method

X-RAY DIFFRACTION (1.8 Å)