3IRR

Crystal Structure of a Z-Z junction (with HEPES intercalating)

Summary for 3IRR

• Entry DOI: 10.2210/pdb3irr/pdb
• Related: 1QBJ 3IRQ
• Descriptor: Double-stranded RNA-specific adenosine deaminase, DNA (5'-D(*G*TP*CP*GP*CP*GP*CP*GP*TP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*A*CP*CP*GP*CP*GP*CP*GP*AP*CP*GP*CP*GP*CP*G)-3'), ... (5 entities in total)
• Functional Keywords: z-dna, adar1, rna editing, innate immunity, dna junction, z domain, intercalation, alternative promoter usage, alternative splicing, cytoplasm, disease mutation, dna-binding, hydrolase, isopeptide bond, metal-binding, mrna processing, nucleus, phosphoprotein, polymorphism, rna-binding, rna-mediated gene silencing, ubl conjugation, zinc, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P55265
• Total number of polymer chains: 6
• Total formula weight: 38912.56

Authors

Athanasiadis, A.,de Rosa, M. (deposition date: 2009-08-24, release date: 2010-05-19, Last modification date: 2023-09-06)

• Primary citation: de Rosa, M.,de Sanctis, D.,Rosario, A.L.,Archer, M.,Rich, A.,Athanasiadis, A.,Carrondo, M.A.; Crystal structure of a junction between two Z-DNA helices.; Proc.Natl.Acad.Sci.USA, 107:9088-9092, 2010; PubMed: 20439751; DOI: 10.1073/pnas.1003182107

Experimental method

X-RAY DIFFRACTION (2.65 Å)