5HSQ
 
 | | The surface engineered photosensory module (PAS-GAF-PHY) of the bacterial phytochrome Agp1 (AtBphP1) in the Pr form, chromophore modelled with an endocyclic double bond in pyrrole ring A. | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome protein, CALCIUM ION, ... | | 著者 | Nagano, S, Scheerer, P, Zubow, K, Lamparter, T, Krauss, N. | | 登録日 | 2016-01-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers.
J.Biol.Chem., 291, 2016
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8F5Z
 | | Composite map of CryoEM structure of Arabidopsis thaliana phytochrome A | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | | 著者 | Li, H, Li, H. | | 登録日 | 2022-11-15 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms.
Nat.Plants, 9, 2023
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5I5L
 | | The photosensory module (PAS-GAF-PHY) of the bacterial phytochrome Agp1 (AtBphP1) in the Pr form, chromophore modelled with an endocyclic double bond in pyrrole ring A | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome protein, CALCIUM ION, ... | | 著者 | Nagano, S, Scheerer, P, Zubow, K, Lamparter, T, Krauss, N. | | 登録日 | 2016-02-15 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers.
J.Biol.Chem., 291, 2016
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5NM3
 | | Deinococcus radiodurans BphP PAS-GAF-PHY Y263F mutant, pre-illuminated | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | | 著者 | Takala, H, Westehoff, S, Ihalainen, J.A. | | 登録日 | 2017-04-05 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome.
J. Biol. Chem., 293, 2018
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6G1Z
 | | Crystal structure of a fluorescence optimized bathy phytochrome PAiRFP2 derived from wild-type Agp2 in its Pfr state. | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, ... | | 著者 | Sauthof, L, Schmidt, A, Szczepek, M, Scheerer, P. | | 登録日 | 2018-03-22 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structural snapshot of a bacterial phytochrome in its functional intermediate state.
Nat Commun, 9, 2018
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8UFI
 | | Cryo-EM structure of bovine phosphodiesterase 6 | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | | 著者 | Aplin, C, Cerione, R.A. | | 登録日 | 2023-10-04 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6.
J.Biol.Chem., 300, 2023
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8ULG
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8UGB
 | | Cryo-EM structure of bovine phosphodiesterase 6 bound to udenafil | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | | 著者 | Aplin, C, Cerione, R.A. | | 登録日 | 2023-10-05 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6.
J.Biol.Chem., 300, 2023
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8UGS
 | | Cryo-EM structure of bovine phosphodiesterase 6 bound to cGMP | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | | 著者 | Aplin, C, Cerione, R.A. | | 登録日 | 2023-10-06 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6.
J.Biol.Chem., 300, 2023
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5NWN
 | | Deinococcus radiodurans BphP PAS-GAF-PHY Y263F mutant, dark | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | | 著者 | Takala, H, Westehoff, S, Ihalainen, J.A. | | 登録日 | 2017-05-07 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome.
J. Biol. Chem., 293, 2018
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5OY5
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3ZQ5
 | | Structure of the Y263F mutant of the cyanobacterial phytochrome Cph1 | | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Mailliet, J, Psakis, G, Sineshchekov, V, Essen, L.-O, Hughes, J. | | 登録日 | 2011-06-07 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Spectroscopy and a High-Resolution Crystal Structure of Tyr263 Mutants of Cyanobacterial Phytochrome Cph1.
J.Mol.Biol., 413, 2011
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3G6O
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8IFF
 | | Cryo-EM structure of Arabidopsis phytochrome A. | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | | 著者 | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | | 登録日 | 2023-02-17 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Plant phytochrome A in the Pr state assembles as an asymmetric dimer.
Cell Res., 33, 2023
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8ISJ
 | | Pr conformer of Arabidopsis thaliana phytochrome A - AtphyA-Pr | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | | 登録日 | 2023-03-20 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor.
Cell Res., 33, 2023
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8ISK
 | | Pr conformer of Zea mays phytochrome A1 - ZmphyA1-Pr | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome | | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | | 登録日 | 2023-03-20 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor.
Cell Res., 33, 2023
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8ISI
 | | Photochromobilin-free form of Arabidopsis thaliana phytochrome A - apo-AtphyA | | 分子名称: | Phytochrome A | | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | | 登録日 | 2023-03-20 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor.
Cell Res., 33, 2023
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6MZB
 | | Cryo-EM structure of phosphodiesterase 6 | | 分子名称: | GUANOSINE-3',5'-MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | | 著者 | Gulati, S, Palczewski, K. | | 登録日 | 2018-11-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases.
Sci Adv, 5, 2019
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6NDO
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193N from Xanthomonas campestris | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Rinaldi, J, Conforte, V, Malamud, F, Goldbaum, F.A, Chavas, L, Bonomi, H.R. | | 登録日 | 2018-12-14 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.58 Å) | | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Febs J., 288, 2021
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6NDP
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193Q from Xanthomonas campestris | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Rinaldi, J, Conforte, V, Malamud, F, Goldbaum, F.A, Chavas, L, Bonomi, H.R. | | 登録日 | 2018-12-14 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Febs J., 288, 2021
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3IBR
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3IBJ
 | | X-ray structure of PDE2A | | 分子名称: | MAGNESIUM ION, ZINC ION, cGMP-dependent 3',5'-cyclic phosphodiesterase | | 著者 | Pandit, J. | | 登録日 | 2009-07-16 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3JBQ
 | | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6 | | 分子名称: | GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ... | | 著者 | Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A. | | 登録日 | 2015-09-17 | | 公開日 | 2015-09-30 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
J.Biol.Chem., 290, 2015
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5AKP
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP from Xanthomonas campestris bound to BV chromophore | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BILIVERDINE IX ALPHA, CHLORIDE ION, ... | | 著者 | Otero, L.H, Klinke, S, Goldbaum, F.A, Bonomi, H.R. | | 登録日 | 2015-03-04 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structure of the Full-Length Bacteriophytochrome from the Plant Pathogen Xanthomonas Campestris Provides Clues to its Long-Range Signaling Mechanism.
J.Mol.Biol., 428, 2016
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7JSN
 | | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6 | | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A. | | 登録日 | 2020-08-15 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-03-31 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.
Mol.Cell, 80, 2020
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