8UFI

Cryo-EM structure of bovine phosphodiesterase 6

Summary for 8UFI

Entry DOI	10.2210/pdb8ufi/pdb
EMDB information	42208
Descriptor	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (6 entities in total)
Functional Keywords	phosphodiesterase, gpcr effector enzyme, signaling protein
Biological source	Bos taurus (cattle) More
Total number of polymer chains	4
Total formula weight	218149.73
Authors	Aplin, C.,Cerione, R.A. (deposition date: 2023-10-04, release date: 2024-01-17, Last modification date: 2024-02-07)
Primary citation	Aplin, C.,Cerione, R.A. Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. J.Biol.Chem., 300:105608-105608, 2023 Cited by PubMed: 38159849 DOI: 10.1016/j.jbc.2023.105608 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation