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7BTG
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Crystal structure of DARP, drosophila arginine phosphatase
Descriptor: CHLORIDE ION, GEO10716p1, PHOSPHATE ION
Authors:Lee, H.S, Mo, Y, Ku, B, Kim, S.J.
Deposit date:2020-04-01
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.188 Å)
Cite:Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1.
Mol.Cells, 43, 2020
1LJU
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BU of 1lju by Molmil
X-RAY STRUCTURE OF C15A ARSENATE REDUCTASE FROM PI258 COMPLEXED WITH ARSENITE
Descriptor: POTASSIUM ION, arsenate reductase
Authors:Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J.
Deposit date:2002-04-22
Release date:2002-08-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
6U1P
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BU of 6u1p by Molmil
Crystal structure of VpsU (VC0916) from Vibrio cholerae
Descriptor: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase
Authors:Tripathi, S.M, Schwechheimer, C, Herbert, K, Osorio, J, Yildiz, F.H, Rubin, S.M.
Deposit date:2019-08-16
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae.
Plos Pathog., 16, 2020
3N8I
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BU of 3n8i by Molmil
Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID
Authors:Homan, K.T, Balasubramaniam, D, Stauffacher, C.V.
Deposit date:2010-05-28
Release date:2011-12-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases
To be Published
7KH8
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BU of 7kh8 by Molmil
Human LMPTP in complex with inhibitor
Descriptor: 3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine, Low molecular weight phosphotyrosine protein phosphatase, NITRATE ION
Authors:Stanford, S.M, Diaz, M.A, Ardecky, R.J, Zou, J, Roosild, T, Holmes, Z.J, Hedrick, M.P, Rodiles, S, Santelli, E, Chung, T.D.Y, Jackson, M.R, Bottini, N, Pinkerton, A.B.
Deposit date:2020-10-20
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase.
J.Med.Chem., 64, 2021
7UW6
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BU of 7uw6 by Molmil
The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2
Descriptor: 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.Y.
Deposit date:2022-05-02
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
J.Med.Chem., 65, 2022
5GOT
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BU of 5got by Molmil
Crystal structure of SP-PTP, low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes
Descriptor: CHLORIDE ION, Low molecular weight phosphotyrosine phosphatase family protein
Authors:Ku, B, Keum, C.W, KIim, S.J.
Deposit date:2016-07-29
Release date:2016-09-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes
Biochem.Biophys.Res.Commun., 478, 2016
5Z3M
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BU of 5z3m by Molmil
Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from Vibrio choleraeO395
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Phosphotyrosine protein phosphatase, ...
Authors:Chatterjee, S, Nath, S, Sen, U.
Deposit date:2018-01-08
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Vibrio cholerae LMWPTP-2 display unique surface charge and grooves around the active site: Indicative of distinctive substrate specificity and scope to design specific inhibitor.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
4PIC
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BU of 4pic by Molmil
YwlE arginine phosphatase from Geobacillus stearothermophilus
Descriptor: Arginine phosphatase Ywle, PHOSPHATE ION, SULFATE ION
Authors:Clausen, T, Fuhrmann, J.
Deposit date:2014-05-08
Release date:2014-05-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap.
Mol.Cell Proteomics, 2014
5KQG
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BU of 5kqg by Molmil
Co-crystal structure of LMW-PTP in complex with 2-(benzothiazol-2-ylamino)-2-oxo-1-phenylethanesulfonic acid
Descriptor: (1~{S})-2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-1-phenyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.-Y, Yu, Z.-H.
Deposit date:2016-07-06
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQM
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Co-crystal structure of LMW-PTP in complex with MES
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.-Y, Yu, Z.-H.
Deposit date:2016-07-06
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
8P5N
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BU of 8p5n by Molmil
Arsenate reductase (ArsC2) from Deinococcus indicus, co-crystallized with arsenate
Descriptor: ARSENATE, GLYCEROL, Low molecular weight phosphatase family protein
Authors:Gouveia, A.G, Matias, P.M, Romao, C.V.
Deposit date:2023-05-24
Release date:2023-08-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus .
Front Microbiol, 14, 2023
8P6M
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BU of 8p6m by Molmil
Arsenate reductase (ArsC2) from Deinococcus indicus
Descriptor: Low molecular weight phosphatase family protein
Authors:Gouveia, A.G, Matias, P.M, Romao, C.V.
Deposit date:2023-05-26
Release date:2023-08-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus .
Front Microbiol, 14, 2023
5KQL
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BU of 5kql by Molmil
Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid
Descriptor: (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.-Y, Yu, Z.-H.
Deposit date:2016-07-06
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQP
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BU of 5kqp by Molmil
Crystal structure of Apo-form LMW-PTP
Descriptor: Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.-Y, Yu, Z.-H.
Deposit date:2016-07-06
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5O7B
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BU of 5o7b by Molmil
CRYSTAL STRUCTURE OF THE SLR0328 TYROSINE PHOSPHATASE WZB FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor: Putative low molecular weight protein-tyrosine-phosphatase slr0328
Authors:Leite, J.P, Gales, L.
Deposit date:2017-06-08
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.281 Å)
Cite:The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803.
Microbiologyopen, 2019
6Y2V
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BU of 6y2v by Molmil
Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, TRIETHYLENE GLYCOL
Authors:Levy, C.
Deposit date:2020-02-17
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme.
Plos One, 15, 2020
4D74
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BU of 4d74 by Molmil
1.57 A crystal structure of erwinia amylovora tyrosine phosphatase amsI
Descriptor: PROTEIN-TYROSINE-PHOSPHATASE AMSI, SULFATE ION
Authors:Benini, S, Salomone-Stagni, M, Caputi, L, Cianci, M.
Deposit date:2014-11-19
Release date:2016-01-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Characterization and 1.57 A Resolution Structure of the Key Fire Blight Phosphatase Amsi from Erwinia Amylovora
Acta Crystallogr.,Sect.F, 72, 2016
5PNT
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BU of 5pnt by Molmil
CRYSTAL STRUCTURE OF A HUMAN LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE. IMPLICATIONS FOR SUBSTRATE SPECIFICITY
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE
Authors:Zhang, M, Stauffacher, C, Lin, D, Vanetten, R.
Deposit date:1998-04-29
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity.
J.Biol.Chem., 273, 1998
1C0E
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BU of 1c0e by Molmil
Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase
Descriptor: PHOSPHATE ION, PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE))
Authors:Tabernero, L, Evans, B.N, Tishmack, P.A, Van Etten, R.L, Stauffacher, C.V.
Deposit date:1999-07-15
Release date:1999-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism.
Biochemistry, 38, 1999
1BVH
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BU of 1bvh by Molmil
SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE
Descriptor: ACID PHOSPHATASE
Authors:Logan, T.M, Zhou, M.-M, Nettesheim, D.G, Meadows, R.P, Van Etten, R.L, Fesik, S.W.
Deposit date:1994-05-03
Release date:1994-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of a low molecular weight protein tyrosine phosphatase.
Biochemistry, 33, 1994
6Y2W
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BU of 6y2w by Molmil
Crystal structure of the single mutant I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Descriptor: ACETATE ION, Low molecular weight phosphotyrosine protein phosphatase
Authors:Levy, C.
Deposit date:2020-02-17
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme.
Plos One, 15, 2020
2WJA
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BU of 2wja by Molmil
Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with phosphate.
Descriptor: NICKEL (II) ION, PHOSPHATE ION, PUTATIVE ACID PHOSPHATASE WZB
Authors:Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H.
Deposit date:2009-05-25
Release date:2009-07-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
2WMY
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BU of 2wmy by Molmil
Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with sulphate.
Descriptor: NICKEL (II) ION, PUTATIVE ACID PHOSPHATASE WZB, SULFATE ION
Authors:Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H.
Deposit date:2009-07-03
Release date:2009-07-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Crystal Structures of the Capsular Export Regulating Tyrosine Phosphatases Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae.
To be Published
4ETM
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BU of 4etm by Molmil
Crystal structure of YfkJ from Bacillus subtilis
Descriptor: Low molecular weight protein-tyrosine-phosphatase yfkJ, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Cao, X.F, Su, X.D.
Deposit date:2012-04-24
Release date:2012-10-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of YfkJ from Bacillus subtilis
To be published

 

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