5Z3M

Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from Vibrio choleraeO395

Summary for 5Z3M

Entry DOI	10.2210/pdb5z3m/pdb
Descriptor	Phosphotyrosine protein phosphatase, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, ... (5 entities in total)
Functional Keywords	phosphatase, ligand bound, hydrolase
Biological source	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Total number of polymer chains	2
Total formula weight	41493.14
Authors	Chatterjee, S.,Nath, S.,Sen, U. (deposition date: 2018-01-08, release date: 2018-09-19, Last modification date: 2023-11-22)
Primary citation	Chatterjee, S.,Nath, S.,Ghosh, B.,Sen, U. Vibrio cholerae LMWPTP-2 display unique surface charge and grooves around the active site: Indicative of distinctive substrate specificity and scope to design specific inhibitor. Biochim Biophys Acta Proteins Proteom, 1867:114-124, 2019 Cited by PubMed: 30447286 DOI: 10.1016/j.bbapap.2018.11.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation