3N8I

Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid

Summary for 3N8I

• Entry DOI: 10.2210/pdb3n8i/pdb
• Related: 3n8j 5PNT
• Descriptor: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID (3 entities in total)
• Functional Keywords: tyrosine phosphatase, hydrolase, protein-ligand complex
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P24666
• Total number of polymer chains: 1
• Total formula weight: 18120.51

Authors

Homan, K.T.,Balasubramaniam, D.,Stauffacher, C.V. (deposition date: 2010-05-28, release date: 2011-12-07, Last modification date: 2023-09-06)

• Primary citation: Homan, K.T.,Balasubramaniam, D.,Stauffacher, C.V.; Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)