8RRR
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8RQM
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8RI9
| Late alpha-Synuclein fibril structure from liquid-liquid phase separations. | 分子名称: | Alpha-synuclein | 著者 | De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G. | 登録日 | 2023-12-18 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates. J.Am.Chem.Soc., 146, 2024
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8OQI
| Cryo-EM structure of the wild-type alpha-synuclein fibril. | 分子名称: | Alpha-synuclein | 著者 | Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G. | 登録日 | 2023-04-12 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease. Brain, 147, 2024
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8JEY
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8JEX
| Cryo-EM structure of alpha-synuclein gS87 fibril | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein, unverified amino acid chain | 著者 | Xia, W.C, Sun, Y.P, Liu, C. | 登録日 | 2023-05-16 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures. Nat Commun, 15, 2024
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8HZS
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8HZC
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8HZB
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8H05
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8H04
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8H03
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8GF7
| Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein | 著者 | Balana, J.A, Nguyen, A.B, Saelices, L, Pratt, R.M. | 登録日 | 2023-03-07 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | O-GlcNAc forces an alpha-synuclein amyloid strain with notably diminished seeding and pathology. Nat.Chem.Biol., 20, 2024
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8FPT
| STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | 分子名称: | Alpha-synuclein | 著者 | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | 登録日 | 2023-01-05 | 公開日 | 2023-02-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Biorxiv, 2023
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8CZ6
| CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CZ3
| CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CZ2
| CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CZ1
| CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CZ0
| CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYY
| CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYX
| CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYW
| CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYV
| CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYT
| CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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8CYS
| CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I | 分子名称: | Alpha-synuclein | 著者 | Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
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