8JEX

Cryo-EM structure of alpha-synuclein gS87 fibril

Summary for 8JEX

• Entry DOI: 10.2210/pdb8jex/pdb
• EMDB information: 36202
• Descriptor: Alpha-synuclein, unverified amino acid chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: protein fibril, amyloid
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 92887.64

Authors

Xia, W.C.,Sun, Y.P.,Liu, C. (deposition date: 2023-05-16, release date: 2024-04-17)

• Primary citation: Hu, J.,Xia, W.,Zeng, S.,Lim, Y.J.,Tao, Y.,Sun, Y.,Zhao, L.,Wang, H.,Le, W.,Li, D.,Zhang, S.,Liu, C.,Li, Y.M.; Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures; Nat Commun, 15:2677-, 2024; DOI: 10.1038/s41467-024-46898-1

Experimental method

ELECTRON MICROSCOPY (3.1 Å)