8JEX
Cryo-EM structure of alpha-synuclein gS87 fibril
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| H | ASP2 | |
| H | HIS50 | |
| P | ASP2 | |
| P | HIS50 | |
| G | ASP2 | |
| G | HIS50 | |
| B | ASP2 | |
| B | HIS50 | |
| K | ASP2 | |
| K | HIS50 | |
| A | ASP2 | |
| A | HIS50 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:22407793 |
| Chain | Residue | Details |
| H | MET1 | |
| P | MET1 | |
| G | MET1 | |
| B | MET1 | |
| K | MET1 | |
| A | MET1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:10617630 |
| Chain | Residue | Details |
| H | SER87 | |
| P | SER87 | |
| G | SER87 | |
| B | SER87 | |
| K | SER87 | |
| A | SER87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:11162638, ECO:0000269|PubMed:12893833 |
| Chain | Residue | Details |
| H | TYR125 | |
| P | TYR125 | |
| G | TYR125 | |
| B | TYR125 | |
| K | TYR125 | |
| A | TYR125 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by BARK1, PLK2, CK2, CK1 and GRK5 => ECO:0000269|PubMed:10617630, ECO:0000269|PubMed:11813001, ECO:0000269|PubMed:24936070 |
| Chain | Residue | Details |
| H | SER129 | |
| P | SER129 | |
| G | SER129 | |
| B | SER129 | |
| K | SER129 | |
| A | SER129 |
