1FIM
 
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1MIF
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1GIF
 | | HUMAN GLYCOSYLATION-INHIBITING FACTOR | | 分子名称: | GLYCOSYLATION-INHIBITING FACTOR | | 著者 | Kato, Y, Kuroki, R. | | 登録日 | 1996-02-27 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded beta-sheets.
Proc.Natl.Acad.Sci.USA, 93, 1996
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1DPT
 | | D-DOPACHROME TAUTOMERASE | | 分子名称: | D-DOPACHROME TAUTOMERASE | | 著者 | Sugimoto, H, Taniguchi, M, Nakagawa, A, Tanaka, I. | | 登録日 | 1998-05-11 | | 公開日 | 1999-03-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.
Biochemistry, 38, 1999
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1CGQ
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1P1G
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1MFI
 | | CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE | | 分子名称: | 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE, PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR) | | 著者 | Taylor, A.B, Johnson Jr, W.H, Czerwinski, R.M, Whitman, C.P, Hackert, M.L. | | 登録日 | 1998-08-12 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
Biochemistry, 38, 1999
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1CA7
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1MFF
 | | MACROPHAGE MIGRATION INHIBITORY FACTOR Y95F MUTANT | | 分子名称: | MACROPHAGE MIGRATION INHIBITORY FACTOR | | 著者 | Taylor, A.B, Stamps, S.L, Wang, S.C, Hackert, M.L, Whitman, C.P. | | 登録日 | 1998-10-19 | | 公開日 | 1999-07-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants.
Biochemistry, 39, 2000
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1GCZ
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1GD0
 | | HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | | 分子名称: | CITRIC ACID, MACROPHAGE MIGRATION INHIBITORY FACTOR, SULFATE ION | | 著者 | Kurihara, H, Katayama, N. | | 登録日 | 2000-08-24 | | 公開日 | 2001-02-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.
J.Med.Chem., 44, 2001
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1HFO
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1LJT
 | | Crystal Structure of Macrophage Migration Inhibitory Factor complexed with (S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole-acetic acid methyl ester (ISO-1) | | 分子名称: | 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER, Macrophage migration inhibitory factor | | 著者 | Lubetsky, J.B, Dios, A, Han, J, Aljabari, B, Ruzsicska, B, Mitchell, R, Lolis, E, Al-Abed, Y. | | 登録日 | 2002-04-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents
J.Biol.Chem., 277, 2002
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1UIZ
 | | Crystal Structure Of Macrophage Migration Inhibitory Factor From Xenopus Laevis. | | 分子名称: | Macrophage Migration Inhibitory Factor | | 著者 | Suzuki, M, Takamura, Y, Maeno, M, Tochinai, S, Iyaguchi, D, Tanaka, I, Nishihira, J, Ishibashi, T. | | 登録日 | 2003-07-24 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Xenopus laevis Macrophage Migration Inhibitory Factor Is Essential for Axis Formation and Neural Development.
J.Biol.Chem., 279, 2004
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2GDG
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2OOW
 | | MIF Bound to a Fluorinated OXIM Derivative | | 分子名称: | 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Crichlow, G.V, Al-Abed, Y, Lolis, E. | | 登録日 | 2007-01-26 | | 公開日 | 2007-06-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
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2OOZ
 | | Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group) | | 分子名称: | 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Crichlow, G.V, Al-Abed, Y, Lolis, E. | | 登録日 | 2007-01-26 | | 公開日 | 2007-06-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
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2OOH
 | | Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11 | | 分子名称: | 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, Macrophage migration inhibitory factor, ... | | 著者 | Crichlow, G.V, Al-Abed, Y, Lolis, E. | | 登録日 | 2007-01-25 | | 公開日 | 2007-06-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
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2OS5
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3B64
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3B9S
 | | Macrophage Migration Inhibitory Factor (MIF) complexed with Inhibitor, 4-IPP. | | 分子名称: | 4-phenylpyrimidine, GLYCEROL, Macrophage Migration Inhibitory Factor, ... | | 著者 | Zierow, S, Crichlow, G, Lolis, E. | | 登録日 | 2007-11-06 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.
Cancer Res., 68, 2008
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3DJH
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3DJI
 | | Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived from NAPQI | | 分子名称: | CHLORIDE ION, Macrophage migration inhibitory factor, N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide | | 著者 | Crichlow, G.V, Lolis, E. | | 登録日 | 2008-06-23 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
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3CE4
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3FWT
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