2OOZ
Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group)
Summary for 2OOZ
Entry DOI | 10.2210/pdb2ooz/pdb |
Related | 2OOH 2OOW |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME, ... (6 entities in total) |
Functional Keywords | alternative ligand-binding modes, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted : P14174 |
Total number of polymer chains | 3 |
Total formula weight | 38352.42 |
Authors | Crichlow, G.V.,Al-Abed, Y.,Lolis, E. (deposition date: 2007-01-26, release date: 2007-06-05, Last modification date: 2023-08-30) |
Primary citation | Crichlow, G.V.,Cheng, K.F.,Dabideen, D.,Ochani, M.,Aljabari, B.,Pavlov, V.A.,Miller, E.J.,Lolis, E.,Al-Abed, Y. Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor. J.Biol.Chem., 282:23089-23095, 2007 Cited by PubMed: 17526494DOI: 10.1074/jbc.M701825200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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