PDB: 59 resultsInfo pagesStatus searchChemie searchBIRD

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3J98	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... Authors: Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. Deposit date: 2014-12-05 Release date: 2015-01-28 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (8.4 Å) Cite: Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
3J97	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II) Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... Authors: Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. Deposit date: 2014-12-05 Release date: 2015-01-28 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (7.8 Å) Cite: Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
2N1T	Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution Descriptor: Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ... Authors: Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J. Deposit date: 2015-04-21 Release date: 2015-06-03 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nat.Struct.Mol.Biol., 22, 2015
5BV0	Crystal Structure of a Complex Between the SNARE Nyv1 and the HOPS Vps33-Vps16 subcomplex from Chaetomium thermophilum Descriptor: SM (Sec1/Munc18-like) protein, SNARE domain, Vps16 Authors: Baker, R.W, Jeffrey, P.D, Hughson, F.M. Deposit date: 2015-06-04 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science, 349, 2015
5CCI	Structure of the Mg2+-bound synaptotagmin-1 SNARE complex (short unit cell form) Descriptor: MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Zhou, Q, Zhao, M, Lyubimov, A.Y, Uervirojnangkoorn, M, Weis, W.I, Brunger, A.T. Deposit date: 2015-07-02 Release date: 2015-08-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525, 2015
5CCH	Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (short unit cell form) Descriptor: CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Zhou, Q, Zhao, M, Lyubimov, A.Y, Uervirojnangkoorn, M, Zeldin, O.B, Weis, W.I, Brunger, A.T. Deposit date: 2015-07-02 Release date: 2015-08-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525, 2015
5CCG	Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) Descriptor: CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Zhou, Q, Zhao, M, Lyubimov, A.Y, Uervirojnangkoorn, M, Zeldin, O.B, Weis, W.I, Brunger, A.T. Deposit date: 2015-07-02 Release date: 2015-08-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525, 2015
5KJ7	Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from XFEL diffraction Descriptor: CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Lyubimov, A.Y, Uervirojnangkoorn, M, Zhou, Q, Zhao, M, Sauter, N.K, Brewster, A.S, Weis, W.I, Brunger, A.T. Deposit date: 2016-06-17 Release date: 2016-10-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex. Elife, 5, 2016
5KJ8	Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from synchrotron diffraction Descriptor: CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Lyubimov, A.Y, Uervirojnangkoorn, M, Zhou, Q, Zhao, M, Sauter, N.K, Brewster, A.S, Weis, W.I, Brunger, A.T. Deposit date: 2016-06-17 Release date: 2016-10-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex. Elife, 5, 2016
5VNG	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal II sorting motif Descriptor: C-terminal ILE-ILE, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Method: X-RAY DIFFRACTION (2.6 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNM	Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (15mM soaking) Descriptor: 4-PHENYL-BUTANOIC ACID, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.765 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNH	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal SV sorting motif Descriptor: C-terminal SV motif, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNK	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal LL sorting motif Descriptor: C-terminal LL, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.55 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNE	Crystal structure of Sec23a/Sec24a/Sec22 complexed with Emp24 sorting motif Descriptor: EMP24, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.698 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNI	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FA sorting motif Descriptor: C-terminal FA, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.788 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNL	Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (1mM soaking) Descriptor: 4-PHENYL-BUTANOIC ACID, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.394 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNF	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif Descriptor: C-terminal VV Sorting motif: VAL-THR-SER-VAL-VAL, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.407 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNJ	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FF sorting motif (ERGIC-53) Descriptor: C-terminal FF Ergic-53, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.806 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNN	Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (50mM soaking) Descriptor: 4-PHENYL-BUTANOIC ACID, Protein transport protein Sec23A, Protein transport protein Sec24A, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-05-01 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.501 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5VNO	Crystal structure of Sec23a/Sec24a/Sec22 Descriptor: Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... Authors: Ma, W, Goldberg, J. Deposit date: 2017-05-01 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.905 Å) Cite: ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5W5D	Crystal structure of the primed SNARE-Complexin-Synaptotagmin-1 C2B complex Descriptor: Complexin-1, MAGNESIUM ION, Synaptosomal-associated protein 25, ... Authors: Zhou, Q, Brunger, A.T. Deposit date: 2017-06-14 Release date: 2017-08-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.496 Å) Cite: The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature, 548, 2017
5W5C	Crystal structure of the primed SNARE-Complexin-Synaptotagmin-1 C2AB complex Descriptor: Complexin-1, GLYCEROL, MAGNESIUM ION, ... Authors: Zhou, Q, Brunger, A.T. Deposit date: 2017-06-14 Release date: 2017-08-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature, 548, 2017
6MDN	The 20S supercomplex engaging the SNAP-25 N-terminus (class 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ... Authors: White, K.I, Zhao, M, Brunger, A.T. Deposit date: 2018-09-04 Release date: 2018-09-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
6MDM	The 20S supercomplex engaging the SNAP-25 N-terminus (class 1) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ... Authors: White, K.I, Zhao, M, Brunger, A.T. Deposit date: 2018-09-04 Release date: 2018-09-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
6MTI	Synaptotagmin-1 C2A, C2B domains and SNARE-pin proteins (5CCI) individually docked into Cryo-EM map of C2AB-SNARE complexes helically organized on lipid nanotube surface in presence of Mg2+ Descriptor: MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Grushin, K, Wang, J, Coleman, J, Rothman, J, Sindelar, C, Krishnakumar, S. Deposit date: 2018-10-19 Release date: 2019-04-24 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (10.4 Å) Cite: Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin. Nat Commun, 10, 2019

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