5VNF

Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif

Summary for 5VNF

Entry DOI	10.2210/pdb5vnf/pdb
Related	5VNE 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Descriptor	Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... (6 entities in total)
Functional Keywords	copii, trafficking, p24, er retention, protein transport
Biological source	Homo sapiens (Human) More
Cellular location	Smooth endoplasmic reticulum membrane; Peripheral membrane protein: Q15436 Cytoplasm : O95486 Endoplasmic reticulum membrane ; Single-pass type IV membrane protein : O08547
Total number of polymer chains	4
Total formula weight	189181.29
Authors	Ma, W.,Goldberg, J. (deposition date: 2017-04-30, release date: 2017-07-05, Last modification date: 2024-03-13)
Primary citation	Ma, W.,Goldberg, E.,Goldberg, J. ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6:-, 2017 Cited by PubMed: 28594326 DOI: 10.7554/eLife.26624 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.407 Å)

Structure validation