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5CCH

Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (short unit cell form)

Summary for 5CCH
Entry DOI10.2210/pdb5cch/pdb
Related5CCG 5CCI
DescriptorVesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, ... (6 entities in total)
Functional Keywordssynaptic fusion complex, synaptotagmin1, neuronal snare complex, endocytosis, exocytosis
Biological sourceRattus norvegicus (Rat)
More
Cellular locationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein: P63045 P32851
Cytoplasm, perinuclear region : P60881 P60881
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21707
Total number of polymer chains6
Total formula weight96345.44
Authors
Zhou, Q.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Weis, W.I.,Brunger, A.T. (deposition date: 2015-07-02, release date: 2015-08-12, Last modification date: 2023-09-27)
Primary citationZhou, Q.,Lai, Y.,Bacaj, T.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Brewster, A.S.,Sauter, N.K.,Cohen, A.E.,Soltis, S.M.,Alonso-Mori, R.,Chollet, M.,Lemke, H.T.,Pfuetzner, R.A.,Choi, U.B.,Weis, W.I.,Diao, J.,Sudhof, T.C.,Brunger, A.T.
Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.
Nature, 525:62-67, 2015
Cited by
PubMed: 26280336
DOI: 10.1038/nature14975
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.6 Å)
Structure validation

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