5NDE
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5N4T
| VIM-2 metallo-beta-lactamase in complex with ((S)-3-mercapto-2-methylpropanoyl)-L-tryptophan (Compound 4) | 分子名称: | (2~{S})-3-(1~{H}-indol-3-yl)-2-[[(2~{S})-2-methyl-3-sulfanyl-propanoyl]amino]propanoic acid, BENZOIC ACID, Beta-lactamase VIM-2, ... | 著者 | Li, G.-B, Brem, J, McDonough, M.A, Schofield, C.J. | 登録日 | 2017-02-11 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-beta-lactamase inhibition. Chem. Commun. (Camb.), 53, 2017
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5NJW
| Crystal Structure of BJP-1 metallo beta-lactamase in complex with boric acid | 分子名称: | 1,2-ETHANEDIOL, BORIC ACID, Blr6230 protein, ... | 著者 | Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S. | 登録日 | 2017-03-29 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Boric acid and acetate anion binding to subclass B3 metallo-Beta-lactamase BJP-1 provides clues for mechanism of action and inhibitor design Inorg.Chim.Acta., 2017
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5NGG
| Crystal structure of the subclass B3 metallo-beta-lactamase BJP-1 in complex with acetate anion | 分子名称: | ACETATE ION, Blr6230 protein, ZINC ION | 著者 | Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S. | 登録日 | 2017-03-17 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Boric acid and acetate anion binding to subclass B3 metallo-Beta-lactamase BJP-1 provides clues for mechanism of action and inhibitor design Inorg.Chim.Acta., 2017
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5NI0
| VIM-2_10c. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding | 分子名称: | Beta-lactamase class B VIM-2, ZINC ION, [(2~{R})-1-ethanoylsulfanyl-6-phenyl-hexan-2-yl]phosphonic acid | 著者 | Skagseth, S, Akhter, S, Paulsen, M.H, Samuelsen, O, Muhammad, Z, Leiros, H.-K.S, Bayer, A. | 登録日 | 2017-03-22 | 公開日 | 2017-04-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.673 Å) | 主引用文献 | Metallo-beta-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding. Eur J Med Chem, 135, 2017
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5O2E
| Crystal structure of NDM-1 in complex with hydrolyzed cefuroxime - new refinement | 分子名称: | (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase type 2, SULFATE ION, ... | 著者 | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A. | 登録日 | 2017-05-20 | 公開日 | 2018-12-26 | 最終更新日 | 2023-02-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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5O7N
| Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid | 分子名称: | (2~{R})-1-[(2~{S})-2-(phenylmethyl)-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase VIM-2, ... | 著者 | Buettner, D, Kramer, J.S, Pogoryelov, D, Proschak, E. | 登録日 | 2017-06-09 | 公開日 | 2018-06-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-beta-Lactamases. Acs Infect Dis., 4, 2018
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5O2F
| Crystal structure of NDM-1 in complex with hydrolyzed ampicillin - new refinement | 分子名称: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A. | 登録日 | 2017-05-20 | 公開日 | 2018-12-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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3VPE
| Crystal Structure of Metallo-beta-Lactamase SMB-1 | 分子名称: | ACETATE ION, GLYCEROL, Metallo-beta-lactamase, ... | 著者 | Wachino, J, Yamaguchi, Y, Mori, S, Arakawa, Y, Shibayama, K. | 登録日 | 2012-02-29 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Subclass B3 Metallo-beta-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor Mercaptoacetate Antimicrob.Agents Chemother., 57, 2013
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3VQZ
| Crystal structure of metallo-beta-lactamase, SMB-1, in a complex with mercaptoacetic acid | 分子名称: | Metallo-beta-lactamase, SODIUM ION, SULFANYLACETIC ACID, ... | 著者 | Wachino, J, Yamaguchi, Y, Mori, S, Arakawa, Y, Shibayama, K. | 登録日 | 2012-04-02 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Insights into the Subclass B3 Metallo-beta-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor Mercaptoacetate Antimicrob.Agents Chemother., 57, 2013
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3WXC
| Crystal Structure of IMP-1 metallo-beta-lactamase complexed with a 3-aminophtalic acid inhibitor | 分子名称: | 3-(4-hydroxypiperidin-1-yl)benzene-1,2-dicarboxylic acid, Beta-lactamase, ZINC ION | 著者 | Saito, J, Watanabe, T, Yamada, M. | 登録日 | 2014-07-29 | 公開日 | 2014-10-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystallographic analysis of IMP-1 metallo-beta-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors Bioorg.Med.Chem.Lett., 24, 2014
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3X2Y
| Crystal structure of metallo-beta-lactamase H8A from Thermotoga maritima | 分子名称: | NICKEL (II) ION, UPF0173 metal-dependent hydrolase TM_1162 | 著者 | Choi, H.J, Kim, H.J, Matsuura, A, Mikami, B, Yoon, H.J, Lee, H.H. | 登録日 | 2015-01-07 | 公開日 | 2016-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of metallo-beta-lactamase H8A from Thermotoga maritima To be Published
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3X30
| Crystal structure of metallo-beta-lactamase from Thermotoga maritima | 分子名称: | MANGANESE (II) ION, NICKEL (II) ION, UPF0173 metal-dependent hydrolase TM_1162 | 著者 | Choi, H.J, Kim, H.J, Matsuura, A, Mikami, B, Yoon, H.J, Lee, H.H. | 登録日 | 2015-01-07 | 公開日 | 2016-02-17 | 実験手法 | X-RAY DIFFRACTION (1.921 Å) | 主引用文献 | Crystal structure of metallo-beta-lactamase from Thermotoga maritima To be Published
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3X2X
| Crystal structure of metallo-beta-lactamase H48A from Thermotoga maritima | 分子名称: | MANGANESE (II) ION, UPF0173 metal-dependent hydrolase TM_1162 | 著者 | Choi, H.J, Kim, H.J, Matsuura, A, Mikami, B, Yoon, H.J, Lee, H.H. | 登録日 | 2015-01-07 | 公開日 | 2016-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Crystal structure of metallo-beta-lactamase H48A from Thermotoga maritima To be Published
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3X2Z
| Crystal structure of metallo-beta-lactamase in complex with nickel from Thermotoga maritima | 分子名称: | NICKEL (II) ION, UPF0173 metal-dependent hydrolase TM_1162 | 著者 | Choi, H.J, Kim, H.J, Matsuura, A, Mikami, B, Yoon, H.J, Lee, H.H. | 登録日 | 2015-01-07 | 公開日 | 2016-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystal structure of metallo-beta-lactamase in complex with nickel from Thermotoga maritima To be Published
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3ZR9
| Structure of New Delhi Metallo-Beta-lactamase 1 (NDM-1) | 分子名称: | BETA-LACTAMASE NDM-1, CADMIUM ION, COBALT (II) ION, ... | 著者 | Green, V.L, Verma, A, Owens, R.J, Phillips, S.E.V, Carr, S.B. | 登録日 | 2011-06-15 | 公開日 | 2011-06-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structure of New Delhi Metallo-Beta-Lactamase 1 (Ndm-1). Acta Crystallogr.,Sect.F, 67, 2011
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3ZWF
| Crystal structure of Human tRNase Z, short form (ELAC1). | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, SODIUM ION, ... | 著者 | Allerston, C.K, Krojer, T, Berridge, G, Burgess-Brown, N, Chaikuad, A, Chalk, R, Elkins, J.M, Gileadi, C, Latwiel, S.V.A, Savitsky, P, Vollmar, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O. | 登録日 | 2011-07-29 | 公開日 | 2011-08-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Human Trnase Z, Short Form (Elac1). To be Published
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4AWZ
| Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 | 分子名称: | CALCIUM ION, MAGNESIUM ION, METALLO-BETA-LACTAMASE AIM-1, ... | 著者 | Leiros, H.-K.S, Borra, P.S, Brandsdal, B.O, Edvardsen, K.S.W, Spencer, J, Walsh, T.R, Samuelsen, O. | 登録日 | 2012-06-06 | 公開日 | 2012-06-20 | 最終更新日 | 2012-08-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157. Antimicrob.Agents Chemother., 56, 2012
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4AX1
| Q157N mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 | 分子名称: | ACETATE ION, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Leiros, H.-K.S, Borra, P.S, Brandsdal, B.O, Edvardsen, K.S.W, Spencer, J, Walsh, T.R, Samuelsen, O. | 登録日 | 2012-06-06 | 公開日 | 2012-06-20 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56, 2012
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4AX0
| Q157A mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 | 分子名称: | ACETATE ION, CALCIUM ION, METALLO-BETA-LACTAMASE AIM-1, ... | 著者 | Leiros, H.-K.S, Borra, P.S, Brandsdal, B.O, Edvardsen, K.S.W, Spencer, J, Walsh, T.R, Samuelsen, O. | 登録日 | 2012-06-06 | 公開日 | 2012-06-20 | 最終更新日 | 2018-06-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56, 2012
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4AWY
| Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 | 分子名称: | CALCIUM ION, MAGNESIUM ION, METALLO-BETA-LACTAMASE AIM-1, ... | 著者 | Leiros, H.-K.S, Borra, P.S, Brandsdal, B.O, Edvardsen, K.S.W, Spencer, J, Walsh, T.R, Samuelsen, O. | 登録日 | 2012-06-06 | 公開日 | 2012-06-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56, 2012
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7DCK
| Crystal structure of phosphodiesterase tw9814 | 分子名称: | Lactamase_B domain-containing protein, MANGANESE (II) ION | 著者 | Heo, Y, Yun, J.H, Park, J.H, Park, S.B, Cha, S.S, Lee, W. | 登録日 | 2020-10-26 | 公開日 | 2021-10-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural and functional identification of the uncharacterized metallo-beta-lactamase superfamily protein TW9814 as a phosphodiesterase with unique metal coordination. Acta Crystallogr D Struct Biol, 78, 2022
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7DTN
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7DTM
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7DV0
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