4AX1
Q157N mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Summary for 4AX1
Entry DOI | 10.2210/pdb4ax1/pdb |
Related | 4AWY 4AWZ 4AX0 |
Descriptor | METALLO-BETA-LACTAMASE AIM-1, ZINC ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance, acquired b3, drug binding site |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 1 |
Total formula weight | 32224.52 |
Authors | Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. (deposition date: 2012-06-06, release date: 2012-06-20, Last modification date: 2019-10-16) |
Primary citation | Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56:4341-, 2012 Cited by PubMed: 22664968DOI: 10.1128/AAC.00448-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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