4AX0

Q157A mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157

Summary for 4AX0

Entry DOI	10.2210/pdb4ax0/pdb
Related	4AWY 4AWZ 4AX1
Descriptor	METALLO-BETA-LACTAMASE AIM-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, acquired b3, drug binding site
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	1
Total formula weight	32132.89
Authors	Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. (deposition date: 2012-06-06, release date: 2012-06-20, Last modification date: 2018-06-20)
Primary citation	Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56:4341-, 2012 Cited by PubMed: 22664968 DOI: 10.1128/AAC.00448-12 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation