4AWY

Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157

Summary for 4AWY

Entry DOI	10.2210/pdb4awy/pdb
Related	4AWZ 4AX0 4AX1
Descriptor	METALLO-BETA-LACTAMASE AIM-1, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, acquired b3, drug binding site, intramolecular disulphide bridges
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	1
Total formula weight	32253.45
Authors	Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. (deposition date: 2012-06-06, release date: 2012-06-20, Last modification date: 2023-12-20)
Primary citation	Leiros, H.-K.S.,Borra, P.S.,Brandsdal, B.O.,Edvardsen, K.S.W.,Spencer, J.,Walsh, T.R.,Samuelsen, O. Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56:4341-, 2012 Cited by PubMed: 22664968 DOI: 10.1128/AAC.00448-12 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation