7DTM

Crystal structure of metallo-beta-lactamase IMP-1 in complex with citrate.

Summary for 7DTM

Entry DOI	10.2210/pdb7dtm/pdb
Descriptor	Metallo-beta-lactamase type 2, ZINC ION, CITRATE ANION, ... (4 entities in total)
Functional Keywords	metallo-beta-lactamase, zinc(ii) ion, citrate, hydrolase
Biological source	Serratia marcescens
Total number of polymer chains	4
Total formula weight	101866.38
Authors	Yamaguchi, Y.,Kurosaki, H. (deposition date: 2021-01-06, release date: 2021-08-04, Last modification date: 2023-11-29)
Primary citation	Yamaguchi, Y.,Kato, K.,Ichimaru, Y.,Jin, W.,Sakai, M.,Abe, M.,Wachino, J.I.,Arakawa, Y.,Miyagi, Y.,Imai, M.,Fukuishi, N.,Yamagata, Y.,Otsuka, M.,Fujita, M.,Kurosaki, H. Crystal Structures of Metallo-beta-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester. J.Med.Chem., 64:10019-10026, 2021 Cited by PubMed: 34242022 DOI: 10.1021/acs.jmedchem.1c00308 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation