PDB: 657 resultsInfo pagesStatus searchChemie searchBIRD

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4RR1	re-refinement of entry 1sot, Crystal Structure of the DegS stress sensor Descriptor: NICKEL (II) ION, PHOSPHATE ION, Protease degS Authors: Sauer, R.T, Grant, R.A. Deposit date: 2014-11-05 Release date: 2015-03-11 Last modified: 2015-03-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases. Structure, 23, 2015
4YYX	Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin2 C-terminal tail Descriptor: FORMIC ACID, Tight junction protein ZO-1 fused with Claudin-2 C-terminal Authors: Nomme, J, Lavie, A. Deposit date: 2015-03-24 Release date: 2015-04-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J.Biol.Chem., 290, 2015
4Q6S	CFTR Associated Ligand (CAL) PDZ bound to biotinylated peptide BT-L-iCAL36 Descriptor: BT-L-iCAL36 peptide, Golgi-associated PDZ and coiled-coil motif-containing protein Authors: Amacher, J.F, Madden, D.R. Deposit date: 2014-04-23 Release date: 2015-04-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Modulator Preferences are Critical Co-Determinants of PDZ Network Wiring To be Published
4NXQ	Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide Descriptor: Contactin-associated protein-like 4 peptide, T-lymphoma invasion and metastasis-inducing protein 1 Authors: Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. Deposit date: 2013-12-09 Release date: 2015-05-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
4NXP	Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) Descriptor: T-lymphoma invasion and metastasis-inducing protein 1 Authors: Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. Deposit date: 2013-12-09 Release date: 2015-05-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
4NXR	Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Neurexin-1 Peptide Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), Neurexin-2-beta Peptide, ... Authors: Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. Deposit date: 2013-12-09 Release date: 2015-05-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
4XHV	Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ... Authors: Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B. Deposit date: 2015-01-06 Release date: 2015-07-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function. Nat Commun, 6, 2015
4R2Z	Molecular Analysis of the PDZ4 Domain of Mouse PDZK1 Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3 Authors: Birrane, G, Kocher, O, Krieger, M. Deposit date: 2014-08-13 Release date: 2015-08-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular Analysis of the PDZ4 domain from Mouse PDZK1 To be Published
4WYU	Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide Descriptor: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU Authors: Ren, J.Q, Pei, H.H, Feng, W. Deposit date: 2014-11-18 Release date: 2015-10-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule. Biochem.J., 468, 2015
4WYT	Crystal Structure of Scribble PDZ34 tandem at 2.6 Angstroms Descriptor: CHLORIDE ION, Protein scribble homolog Authors: Ren, J.Q, Feng, W. Deposit date: 2014-11-18 Release date: 2015-10-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule. Biochem.J., 468, 2015
5E6P	PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11 Authors: Pascoe, H.G, Zhang, X. Deposit date: 2015-10-10 Release date: 2015-11-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.215 Å) Cite: Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF. Proc.Natl.Acad.Sci.USA, 112, 2015
2MX6	Complex structure of Dvl PDZ domain with ligand Descriptor: (PHQ)WV peptide, Segment polarity protein dishevelled homolog DVL-1 Authors: Zhang, X, Zheng, J.J. Deposit date: 2014-12-15 Release date: 2015-12-30 Method: SOLUTION NMR Cite: Protein-ligand interaction decoded by NMR chemical shift analysis To be Published
4Z8J	Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif Descriptor: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27 Authors: Clairfeuille, T, Pavlos, N, Collins, B.M. Deposit date: 2015-04-09 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (0.95 Å) Cite: Role of SNX27-retromer in PTHR trafficking To Be Published
5F67	An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in complex with TRP channel tail Descriptor: Inactivation-no-after-potential D protein, TRP C terminal Tail Authors: Ye, F, Shang, Y, Liu, W, Zhang, M. Deposit date: 2015-12-05 Release date: 2016-02-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.76 Å) Cite: An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail Structure, 24, 2016
5I7Z	Crystal structure of a Par-6 PDZ-Crumbs 3 C-terminal peptide complex Descriptor: Crb-3, DI(HYDROXYETHYL)ETHER, LD29223p Authors: Whitney, D.S, Peterson, F.C, Prehoda, K.E, Volkman, B.F. Deposit date: 2016-02-18 Release date: 2016-03-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Binding of Crumbs to the Par-6 CRIB-PDZ Module Is Regulated by Cdc42. Biochemistry, 55, 2016
5F3X	Crystal structure of Harmonin NPDZ1 in complex with ANKS4B SAM-PBM Descriptor: Ankyrin repeat and SAM domain-containing protein 4B, CHLORIDE ION, Harmonin Authors: Li, J, He, Y, Lu, Q, Zhang, M. Deposit date: 2015-12-03 Release date: 2016-03-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.649 Å) Cite: Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex Dev.Cell, 36, 2016
5A2P	THE COMPLEX STRUCTURE OF PDZ DOMAINS IN SYNTENIN-1 WITH 4L PEPTIDE Descriptor: SYNDECAN-4, SYNTENIN-1 Authors: Yoo, J.H, Yun, J.H, Cho, H.S, Lee, W. Deposit date: 2015-05-21 Release date: 2016-06-01 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.496 Å) Cite: Titl the Complex Structure of Pdz Domains in Syntenin-1 with 4L Peptide To be Published
5EYZ	CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV Descriptor: CHLORIDE ION, CYTO8-RETEV, Tyrosine-protein phosphatase non-receptor type 4 Authors: Maisonneuve, P, Vaney, M.C, Babault, B, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. Deposit date: 2015-11-26 Release date: 2016-06-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
5EZ0	CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA. Descriptor: Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4 Authors: Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. Deposit date: 2015-11-26 Release date: 2016-06-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
5FB8	Structure of Interleukin-16 bound to the 14.1 antibody Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-IL-16 antibody 14.1 Fab domain Heavy Chain, ... Authors: Hall, G, Cowan, R, Bayliss, R, Carr, M. Deposit date: 2015-12-14 Release date: 2016-06-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES. J.Biol.Chem., 291, 2016
4YDP	Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide. Descriptor: GLUTAMIC ACID, LEUCINE, LIM domain-binding protein 3 Authors: Grishkovskaya, I, Onipe, A, Kontaxis, G, Djinovic-Carugo, K. Deposit date: 2015-02-22 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide. To Be Published
4Z33	Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2 Descriptor: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... Authors: Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P. Deposit date: 2015-03-30 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2 To Be Published
5D13	Third PDZ domain (PDZ3) of PSD-95 complexed with CFMOC-KKETEV peptide Descriptor: CFMOC-KKETEV peptide, Disks large homolog 4 Authors: De, S, Spaller, M.R, Olson, R. Deposit date: 2015-08-03 Release date: 2016-08-17 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Chemically-modified peptides as inhibitors of PDZ3 of PSD-95 to be published
5ELQ	Crystal structure of the SNX27 PDZ domain bound to the C-terminal DGKzeta PDZ binding motif Descriptor: GLU-ASP-GLN-GLU-THR-ALA-VAL, Sorting nexin-27, TETRAETHYLENE GLYCOL Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-05 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.1 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EM9	Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif Descriptor: SEP-LEU-GLU-SER-CYS-PHE, Sorting nexin-27 Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-06 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016

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