PDB: 63 resultsInfo pagesStatus searchChemie searchBIRD

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8IJR	The cryo-EM structure of human sphingomyelin synthase-related protein in complex with diacylglycerol/phosphoethanolamine Descriptor: (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, Sphingomyelin synthase-related protein 1 Authors: Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. Deposit date: 2023-02-28 Release date: 2024-02-28 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 2024
8P2M	C. elegans TIR-1 protein. Descriptor: NAD(+) hydrolase tir-1 Authors: Isupov, M.N, Opatowsky, Y. Deposit date: 2023-05-16 Release date: 2023-09-06 Method: ELECTRON MICROSCOPY (3.82 Å) Cite: Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Rep, 42, 2023
5ZRZ	Crystal Structure of EphA5/SAMD5 Complex Descriptor: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5 Authors: Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. Deposit date: 2018-04-25 Release date: 2018-05-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
7KJC	Crystal structure of the EphA2 S901E mutant intracellular KD-SAM domains Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ... Authors: Lechtenberg, B.C, Pasquale, E.B. Deposit date: 2020-10-26 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12, 2021
7KJB	Crystal structure of the EphA2 S897E/S901E mutant intracellular KD-SAM domains Descriptor: CESIUM ION, Ephrin type-A receptor 2 Authors: Lechtenberg, B.C, Pasquale, E.B. Deposit date: 2020-10-26 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12, 2021
7KJA	Crystal structure of the EphA2 intracellular KD-SAM domains Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ... Authors: Lechtenberg, B.C, Pasquale, E.B. Deposit date: 2020-10-26 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12, 2021
8BW8	Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle Authors: Maisonneuve, P, Kurinov, I, Sicheri, F. Deposit date: 2022-12-06 Release date: 2024-02-21 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 2024
3TAD	Crystal Structure of the Liprin-alpha/Liprin-beta complex Descriptor: GLYCEROL, Liprin-alpha-2, Liprin-beta-1 Authors: Wei, Z, Zheng, S, Yu, C, Zhang, M. Deposit date: 2011-08-04 Release date: 2011-10-12 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures Mol.Cell, 43, 2011
1PK1	Hetero SAM domain structure of Ph and Scm. Descriptor: Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA Authors: Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. Deposit date: 2003-06-04 Release date: 2005-02-15 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
6KIP	Crystal structure of PTPRD phosphatase domain in complex with Liprin-alpha3 tandem SAM domains Descriptor: Liprin-alpha-3, Receptor-type tyrosine-protein phosphatase delta Authors: Wakita, M, Yamagata, A, Fukai, S. Deposit date: 2019-07-19 Release date: 2020-02-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.911 Å) Cite: Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-alpha. Nat Commun, 11, 2020
6KR4	Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex Descriptor: HEXAETHYLENE GLYCOL, Liprin-alpha-3, PHOSPHATE ION, ... Authors: Xie, X, Liang, M, Luo, L, Wei, Z. Deposit date: 2019-08-20 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural basis of liprin-alpha-promoted LAR-RPTP clustering for modulation of phosphatase activity. Nat Commun, 11, 2020
8BW9	Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP Descriptor: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ... Authors: Maisonneuve, P, Fronzes, R, Sicheri, F. Deposit date: 2022-12-06 Release date: 2024-02-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 2024
3TAC	Crystal Structure of the Liprin-alpha/CASK complex Descriptor: CHLORIDE ION, Liprin-alpha-2, Peripheral plasma membrane protein CASK, ... Authors: Wei, Z, Zheng, S, Yu, C, Zhang, M. Deposit date: 2011-08-03 Release date: 2011-10-12 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures Mol.Cell, 43, 2011

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