7KJB
Crystal structure of the EphA2 S897E/S901E mutant intracellular KD-SAM domains
Summary for 7KJB
| Entry DOI | 10.2210/pdb7kjb/pdb |
| Descriptor | Ephrin type-A receptor 2, CESIUM ION (3 entities in total) |
| Functional Keywords | eph receptor, kinase, sam, allostery, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 44175.60 |
| Authors | Lechtenberg, B.C.,Pasquale, E.B. (deposition date: 2020-10-26, release date: 2021-02-03, Last modification date: 2023-10-18) |
| Primary citation | Lechtenberg, B.C.,Gehring, M.P.,Light, T.P.,Horne, C.R.,Matsumoto, M.W.,Hristova, K.,Pasquale, E.B. Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12:7047-7047, 2021 Cited by PubMed: 34857764DOI: 10.1038/s41467-021-27343-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report
