5YDX
 
 | |
5XMC
 | |
5VTK
 | | Structure of Pin1 WW Domain Variant 1 with beta3-Ser Loop Substitution | | 分子名称: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
|
|
5VTJ
 | | Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC | | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
|
|
5VTI
 | | Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution | | 分子名称: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
|
|
5UY9
 | | Prolyl isomerase Pin1 R14A mutant bound with Brd4 peptide | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brd4 peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | 著者 | Dong, S.-H, Nair, S. | | 登録日 | 2017-02-23 | | 公開日 | 2017-04-26 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4.
Oncogene, 36, 2017
|
|
5TJQ
 | | Structure of WWP2 2,3-linker-HECT | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Chen, Z, Gabelli, S.B. | | 登録日 | 2016-10-04 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
|
|
5TJ8
 | |
5TJ7
 | |
5O9Z
 | |
5DZD
 | | Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | | 著者 | Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2015-09-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide
To be Published
|
|
5DWS
 | | Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, UNKNOWN ATOM OR ION, txnip | | 著者 | Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2015-09-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide
to be published
|
|
5CQ2
 | | Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2015-07-21 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
|
|
5BMY
 | |
5B3Z
 | |
5B3Y
 | |
5AHT
 | |
4U86
 | | Human Pin1 with cysteine sulfonic acid 113 | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Li, W, Zhang, Y. | | 登録日 | 2014-08-01 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76, 2015
|
|
4U85
 | | Human Pin1 with cysteine sulfinic acid 113 | | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Li, W, Zhang, Y. | | 登録日 | 2014-08-01 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76, 2015
|
|
4U84
 | | Human Pin1 with S-hydroxyl-cysteine 113 | | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Li, W, Zhang, Y. | | 登録日 | 2014-08-01 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76, 2015
|
|
4ROF
 | | Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein | | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide
To be Published
|
|
4REX
 | |
4QIB
 | | Oxidation-Mediated Inhibition of the Peptidyl-Prolyl Isomerase Pin1 | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION | | 著者 | Innes, B.T, Sowole, M.A, Konermann, L, Litchfield, D.W, Brandl, C.J, Shilton, B.H. | | 登録日 | 2014-05-30 | | 公開日 | 2015-02-04 | | 最終更新日 | 2015-03-04 | | 実験手法 | X-RAY DIFFRACTION (1.865 Å) | | 主引用文献 | Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1.
Biochim.Biophys.Acta, 1852, 2015
|
|
4N7H
 | | Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | | 分子名称: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | | 著者 | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | | 登録日 | 2013-10-15 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
|
|
4N7F
 | |
