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4U86

Human Pin1 with cysteine sulfonic acid 113

Summary for 4U86
Entry DOI10.2210/pdb4u86/pdb
Related4U84 4U85
DescriptorPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL (3 entities in total)
Functional Keywordspin1 oxidation isomerase, isomerase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus: Q13526
Total number of polymer chains1
Total formula weight20510.71
Authors
Li, W.,Zhang, Y. (deposition date: 2014-08-01, release date: 2015-04-08, Last modification date: 2023-12-27)
Primary citationChen, C.H.,Li, W.,Sultana, R.,You, M.H.,Kondo, A.,Shahpasand, K.,Kim, B.M.,Luo, M.L.,Nechama, M.,Lin, Y.M.,Yao, Y.,Lee, T.H.,Zhou, X.Z.,Swomley, A.M.,Allan Butterfield, D.,Zhang, Y.,Lu, K.P.
Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76:13-23, 2015
Cited by
PubMed: 25576397
DOI: 10.1016/j.nbd.2014.12.027
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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