5VTI

Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution

Summary for 5VTI

• Entry DOI: 10.2210/pdb5vti/pdb
• Related: 5VTJ 5VTK
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, CHLORIDE ION (3 entities in total)
• Functional Keywords: beta amino acid, ww domain, phosphopeptide binding, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q13526
• Total number of polymer chains: 1
• Total formula weight: 3845.76

Authors

Mortenson, D.E.,Kreitler, D.F.,Thomas, N.C.,Gellman, S.H.,Forest, K.T. (deposition date: 2017-05-17, release date: 2018-02-21, Last modification date: 2023-11-15)

• Primary citation: Mortenson, D.E.,Kreitler, D.F.,Thomas, N.C.,Guzei, I.A.,Gellman, S.H.,Forest, K.T.; Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.; Chembiochem, 19:604-612, 2018; PubMed: 29272560; DOI: 10.1002/cbic.201700580

Experimental method

X-RAY DIFFRACTION (1.8 Å)