5XMC
Crystal structure of the auto-inhibited Nedd4 family E3 ligase Itch
Summary for 5XMC
Entry DOI | 10.2210/pdb5xmc/pdb |
Descriptor | E3 ubiquitin-protein ligase Itchy (2 entities in total) |
Functional Keywords | auto-inhibited itch, ligase |
Biological source | Mus musculus (Mouse) |
Cellular location | Cell membrane : Q8C863 |
Total number of polymer chains | 1 |
Total formula weight | 83412.20 |
Authors | |
Primary citation | Zhu, K.,Shan, Z.,Chen, X.,Cai, Y.,Cui, L.,Yao, W.,Wang, Z.,Shi, P.,Tian, C.,Lou, J.,Xie, Y.,Wen, W. Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch EMBO Rep., 18:1618-1630, 2017 Cited by PubMed: 28747490DOI: 10.15252/embr.201744454 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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