PDB: 107 件ウェブページステータス検索Chemie searchBIRD

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3G8D	Crystal structure of the biotin carboxylase subunit, E296A mutant, of acetyl-COA carboxylase from Escherichia coli 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION, ... 著者 Chou, C.Y, Yu, L.P, Tong, L. 登録日 2009-02-12 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
3GLK	The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) 分子名称: Acetyl-CoA carboxylase 2 著者 Price, A, Kulathila, R. 登録日 2009-03-12 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19, 2009
3HBL	Crystal Structure of S. aureus Pyruvate Carboxylase T908A Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HB9	Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HO8	Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-06-01 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3JZF	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazoles series 分子名称: 2-[(2-chlorobenzyl)amino]-1-(cyclohexylmethyl)-1H-benzimidazole-5-carboxamide, Biotin carboxylase, CARBONATE ION 著者 Orth, P. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
8J4Z	Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... 著者 Liu, D.S, Su, J.Y. 登録日 2023-04-21 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate To Be Published
8J7O	Human pyruvate carboxylase in BCCP-CTS state without BC 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial 著者 Liu, D.S, Su, J.Y. 登録日 2023-04-27 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.83 Å) 主引用文献 Human pyruvate carboxylase To Be Published
8J99	Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state 分子名称: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, Methylcrotonoyl-CoA carboxylase subunit alpha, ... 著者 Liu, D.S, Su, J.Y. 登録日 2023-05-02 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state To Be Published
8J7D	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... 著者 Liu, D.S, Su, J.Y. 登録日 2023-04-27 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state To Be Published
8J78	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... 著者 Liu, D.S, Su, J.Y. 登録日 2023-04-27 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state To Be Published
8PN7	Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... 著者 Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. 登録日 2023-06-30 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.03 Å) 主引用文献 Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase. Acs Synth Biol, 12, 2023
8PN8	Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... 著者 Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. 登録日 2023-06-30 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.31 Å) 主引用文献 Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase. Acs Synth Biol, 12, 2023
8SGZ	Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... 著者 Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. 登録日 2023-04-13 公開日 2023-05-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
8SGY	Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... 著者 Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. 登録日 2023-04-13 公開日 2023-05-17 実験手法 ELECTRON MICROSCOPY (8.62 Å) 主引用文献 CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
8SGX	Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... 著者 Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. 登録日 2023-04-13 公開日 2023-05-17 実験手法 ELECTRON MICROSCOPY (10.3 Å) 主引用文献 CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
8RTH	Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase 分子名称: 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... 著者 Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. 登録日 2024-01-26 公開日 2024-04-17 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.37 Å) 主引用文献 The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function. Structure, 2024
2QF7	Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli 分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ... 著者 St Maurice, M, Surinya, K.H, Rayment, I. 登録日 2007-06-27 公開日 2007-09-04 最終更新日 2012-02-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science, 317, 2007
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 分子名称: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 分子名称: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 分子名称: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. 分子名称: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER 著者 Mochalkin, I, Waldrop, G.L. 登録日 2008-03-24 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment 分子名称: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series 分子名称: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine 分子名称: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009

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