7UJB
| N-terminal domain deletion variant of Eta | 分子名称: | DEAD/DEAH box RNA helicase | 著者 | Qayyum, M.Z, Murakami, K.S. | 登録日 | 2022-03-30 | 公開日 | 2022-08-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.12 Å) | 主引用文献 | The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TRA
| Cascade complex from type I-A CRISPR-Cas system | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | 登録日 | 2022-01-28 | 公開日 | 2022-08-10 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TR8
| Cascade complex from type I-A CRISPR-Cas system | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | 登録日 | 2022-01-28 | 公開日 | 2022-08-10 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TO2
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7TO1
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7TO0
| Cryo-EM structure of RIG-I in complex with OHdsRNA | 分子名称: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | 著者 | Wang, W, Pyle, A.M. | 登録日 | 2022-01-22 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNZ
| Cryo-EM structure of RIG-I in complex with p1dsRNA | 分子名称: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | 著者 | Wang, W, Pyle, A.M. | 登録日 | 2022-01-22 | 公開日 | 2022-11-02 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNY
| Cryo-EM structure of RIG-I in complex with p2dsRNA | 分子名称: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | 著者 | Wang, W, Pyle, A.M. | 登録日 | 2022-01-22 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNX
| Cryo-EM structure of RIG-I in complex with p3dsRNA | 分子名称: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ... | 著者 | Wang, W, Pyle, A.M. | 登録日 | 2022-01-22 | 公開日 | 2022-11-02 | 最終更新日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7SSG
| Mfd DNA complex | 分子名称: | DNA (5'-D(P*TP*GP*GP*CP*GP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*GP*CP*CP*TP*CP*GP*CP*TP*GP*CP*CP*A)-3'), Transcription-repair-coupling factor | 著者 | Oakley, A.J, Xu, Z.-Q. | 登録日 | 2021-11-11 | 公開日 | 2022-05-25 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Mechanism of transcription modulation by the transcription-repair coupling factor. Nucleic Acids Res., 50, 2022
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7S7C
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7S7B
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7R7A
| State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | 分子名称: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | 登録日 | 2021-06-24 | 公開日 | 2022-11-09 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7R72
| State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model | 分子名称: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | 登録日 | 2021-06-24 | 公開日 | 2022-11-09 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7R6Q
| State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | 登録日 | 2021-06-23 | 公開日 | 2022-11-09 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7R2K
| elongated Cascade complex from type I-A CRISPR-Cas system | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | 著者 | Hu, C, Ni, D, Nam, K.H, Terns, M, Stahlberg, H, Ke, A. | 登録日 | 2022-02-04 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural snapshots for an atypic type I CRISPR-Cas system To Be Published
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7QTT
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7QE0
| 80S-bound human SKI complex in the open state | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDZ
| 80S-bound human SKI complex in the closed state | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDY
| RNA-bound human SKI complex | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDS
| Apo human SKI complex in the open state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-30 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDR
| Apo human SKI complex in the closed state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-29 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7Q3L
| Human 17S U2 snRNP 5' domain | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | 著者 | Tholen, J, Galej, W.P. | 登録日 | 2021-10-28 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
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7PX3
| Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-10-07 | 公開日 | 2022-01-26 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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7PQ0
| Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B | 分子名称: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | 著者 | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | 登録日 | 2021-09-15 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1. Commun Biol, 5, 2022
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