PDB: 117 件ウェブページステータス検索Chemie searchBIRD

---

6KDP	Crystal structure of human DNMT3B-DNMT3L complex (II) 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-02 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDB	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-01 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.862 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDT	Crystal structure of human DNMT3B (Q772R)-DNMT3L complex 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-02 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDA	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-01 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.909 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6FDF	Crystal structure of S. pombe Dnmt2 methyltransferase 分子名称: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytosine(38)-C(5))-methyltransferase 著者 Johannsson, S, Neumann, P, Ficner, R. 登録日 2017-12-22 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.697 Å) 主引用文献 Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Sci Rep, 8, 2018
5YX2	Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-12-01 公開日 2018-01-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.653 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
6F57	Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA 分子名称: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-12-01 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.098 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
6BRR	Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-11-30 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
5GUT	The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... 著者 Chen, S.J, Ye, F. 登録日 2016-08-31 公開日 2017-09-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
5GUV	The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D 分子名称: DNA (cytosine-5)-methyltransferase 1, ZINC ION 著者 Ye, F, Chen, S.J. 登録日 2016-08-31 公開日 2017-08-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.078 Å) 主引用文献 Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
5LOD	Crystal structure of HhaI DNA methyltransferase in APO form 分子名称: Modification methylase HhaI, SULFATE ION 著者 Rondelet, G, Wouters, J. 登録日 2016-08-09 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors. Future Med Chem, 9, 2017
5WY1	Crystal structure of mouse DNA methyltransferase 1 (T1505A mutant) 分子名称: DNA (cytosine-5)-methyltransferase 1, ZINC ION 著者 Kanada, K, Takeshita, K, Suetake, I, Tajima, S, Nakagawa, A. 登録日 2017-01-10 公開日 2017-05-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Conserved threonine 1505 in the catalytic domain stabilizes mouse DNA methyltransferase 1 J. Biochem., 162, 2017
5CIY	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain 分子名称: DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... 著者 Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. 登録日 2015-07-13 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.594 Å) 主引用文献 Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
4WXX	The crystal structure of human DNMT1(351-1600) 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Zhang, Z.M, Song, J. 登録日 2014-11-14 公開日 2015-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.622 Å) 主引用文献 Crystal Structure of Human DNA Methyltransferase 1. J.Mol.Biol., 427, 2015
4YOC	Crystal Structure of human DNMT1 and USP7/HAUSP complex 分子名称: DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION 著者 Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. 登録日 2015-03-11 公開日 2015-05-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.916 Å) 主引用文献 Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6, 2015
4U7P	Crystal structure of DNMT3A-DNMT3L complex 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.821 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4ONJ	Crystal structure of the catalytic domain of ntDRM 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4ONQ	Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4DKJ	CpG specific methyltransferase in complex with target DNA 分子名称: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... 著者 Wojciechowski, M, Czapinska, H, Bochtler, M. 登録日 2012-02-03 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI. Proc.Natl.Acad.Sci.USA, 110, 2013
4H0N	Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant 分子名称: CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE 著者 Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J. 登録日 2012-09-09 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.712 Å) 主引用文献 Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol, 5, 2013
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
3UBT	Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA 分子名称: 5'-D(*TP*GP*GP*CP*CP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Verdine, G.L, Didovyk, A. 登録日 2011-10-24 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase. J.Biol.Chem., 287, 2012

<12345>